Results 51 to 60 of about 78,388 (268)

Binding Studies on Isolated Porcine Small Intestinal Mucosa and in vitro Toxicity Studies Reveal Lack of Effect of C. perfringens Beta-Toxin on the Porcine Intestinal Epithelium

Toxins, 2015
Beta-toxin (CPB) is the essential virulence factor of C. perfringens type C causing necrotizing enteritis (NE) in different hosts. Using a pig infection model, we showed that CPB targets small intestinal endothelial cells.
Simone Roos, Marianne Wyder, Ahmet Candi, Nadine Regenscheit, Christina Nathues, Filip van Immerseel, Horst Posthaus   +6 more
doaj   +1 more source

Effect of berberine on LPS-induced expression of NF-κB/MAPK signalling pathway and related inflammatory cytokines in porcine intestinal epithelial cells. [PDF]

Innate Immun, 2020
Berberine is an alkaloid extracted from medicinal plants such as Coptis chinensis and Phellodendron chinense. It possesses anti-inflammatory, anti-tumour and anti-oxidation properties, and regulates Glc and lipid metabolism.
Zhu Z, Xueying L, Chunlin L, Wen X, Rongrong Z, Jing H, Meilan J, Yuwei X, Zili W.   +8 more
europepmc   +2 more sources

Effects of Spermidine on Cell Proliferation, Migration, and Inflammatory Response in Porcine Enterocytes

Frontiers in Bioscience-Landmark, 2022
Background: Polyamines have been demonstrated to be beneficial to porcine intestinal development. Our previous study showed that putrescine mitigates intestinal atrophy in weanling piglets and suppresses inflammatory response in porcine intestinal ...
Zi-xi Wei, Long Cai, Xue-mei Zhao, Xian-ren Jiang, Xi-long Li   +4 more
doaj   +1 more source

Morphogenesis of Porcine Rotavirus in Porcine Kidney Cell Cultures and Intestinal Epithelial Cells

Journal of General Virology, 1978
The morphogenesis of porcine rotavirus was similar in vitro in porcine kidney (PK) cell cultures and in vivo in porcine epithelial cells as examined by electron microscopy. Infected cells contained cytoplasmic, non-membrane-bound viroplasm and accumulations of virus particles within cisternae of the rough endoplasmic reticulum (RER).
L J, Saif, K W, Theil, E H, Bohl
openaire   +2 more sources

L-Glutamate Enhances Barrier and Antioxidative Functions in Intestinal Porcine Epithelial Cells, [PDF]

The Journal of Nutrition, 2015
L-Glutamate (Glu) is a major amino acid in milk and postweaning diets for mammals (including pigs and human infants). However, effects of Glu on intestinal mucosal barrier and antioxidative functions are unknown.This study tested the hypothesis that Glu may enhance the barrier function of intestinal porcine epithelial cell line 1 (IPEC-1) cells by ...
Ning, Jiao, Zhenlong, Wu, Yun, Ji, Bin, Wang, Zhaolai, Dai, Guoyao, Wu   +5 more
openaire   +2 more sources

The Murine Reg3a Stimulated by Lactobacillus casei Promotes Intestinal Cell Proliferation and Inhibits the Multiplication of Porcine Diarrhea Causative Agent in vitro

Frontiers in Microbiology, 2021
Lactobacillus casei (L. casei), a normal resident of the gastrointestinal tract of mammals, has been extensively studied over the past few decades for its probiotic properties in clinical and animal models.
Yongfei Bai, Yanmei Huang, Ying Li, Bingbing Zhang, Cuihong Xiao, Xilin Hou, Liyun Yu   +6 more
doaj   +1 more source

Porcine milk-derived exosomes promote proliferation of intestinal epithelial cells

Scientific Reports, 2016
AbstractMilk-derived exosomes were identified as a novel mechanism of mother-to-child transmission of regulatory molecules, but their functions in intestinal tissues of neonates are not well-studied. Here, we characterized potential roles of porcine milk-derived exosomes in the intestinal tract. In vitro, treatment with milk-derived exosomes (27 ± 3 ng
Ting Chen, Mei-Ying Xie, Jia-Jie Sun, Rui-Song Ye, Xiao Cheng, Rui-Ping Sun, Li-Min Wei, Meng Li, De-Lin Lin, Qing-Yan Jiang, Qian-Yun Xi, Yong-Liang Zhang   +11 more
openaire   +2 more sources

Pyroptosis-Mediated Damage Mechanism by Deoxynivalenol in Porcine Small Intestinal Epithelial Cells

Toxins, 2023
Deoxynivalenol (DON) is known as a vomitoxin, which frequently contaminates feedstuffs, such as corn, wheat, and barley. Intake of DON-contaminated feed has been known to cause undesirable effects, including diarrhea, emesis, reduced feed intake, nutrient malabsorption, weight loss, and delay in growth, in livestock. However, the molecular mechanism of
Tae Hong Kang, Sangsu Shin, JeongWoong Park, Bo Ram Lee, Sang In Lee   +4 more
openaire   +3 more sources

Gene silencing of porcine MUC13 and ITGB5: candidate genes towards Escherichia coli F4ac adhesion. [PDF]

PLoS ONE, 2013
BACKGROUND: Integrin beta-5 (ITGB5) and mucin 13 (MUC13) genes are highly expressed on the apical surface of intestinal epithelia and are thought to be candidate genes for controlling the expression of the receptor for enterotoxigenic Escherichia coli ...
Chuanli Zhou, Zhengzhu Liu, Yang Liu, Weixuan Fu, Xiangdong Ding, Jianfeng Liu, Ying Yu, Qin Zhang   +7 more
doaj   +1 more source

Rapamycin-induced autophagy restricts porcine epidemic diarrhea virus infectivity in porcine intestinal epithelial cells

Antiviral Research, 2017
Porcine epidemic diarrhea virus (PEDV) invades porcine intestinal epithelial cells (IECs) and causes diarrhea and dehydration in pigs. In the present study, we showed a suppression of PEDV infection in porcine jejunum intestinal epithelial cells (IPEC-J2) by an increase in autophagy.
Seongyeol Ko, Min Jeong Gu, Cheol Gyun Kim, Yoon Chul Kye, Younggap Lim, Ji Eun Lee, Byung-Chul Park, Hyuk Chu, Seung Hyun Han, Cheol-Heui Yun   +9 more
openaire   +2 more sources