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Porcine endogenous retrovirus and other viruses in xenotransplantation

Current Opinion in Organ Transplantation, 2009
Potential transmission of zoonotic porcine viruses is a major safety issue in xenotransplantation. This review will first summarize recent studies involving transmission and control of the major concern, porcine endogenous retrovirus (PERV). Second, the potential for zoonotic transfer and safety measures required against other viruses of concern will ...
Scobie, Linda, Takeuchi, Yasuhiro
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Susceptibility of porcine preimplantation embryos to viruses associated with reproductive failure

Theriogenology, 2016
In the modern biological area, the applications of pig as a laboratory model have extensive prospects, such as gene transfer, IVF, SCNT, and xenotransplantation. However, the risk of pathogen transmission by porcine embryos is always a topic to be investigated, especially the viruses related to reproductive failure, for instance, pseudorabies virus ...
Haijing Zhao, Wenjun Wang
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Porcine gastroenteric viruses: pathogenesis and protection

, 2020
The complexity of known porcine coronaviruses (CoVs) has considerably increased. To the classical transmissible gastroenteritis virus (TGEV) known since 1946, its deletion mutant with an exclusive respiratory tropism, the porcine respiratory CoV (PRCV), and the porcine epidemic diarrhea virus (PEDV), several emerging CoVs have been added.
Enjuanes Sánchez, Luis, Pascual-Iglesias, Alejandro, Sánchez, Carlos M., Carlos Zaberezhny, A. D., Zúñiga Lucas, Sonia   +4 more
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Frequency detection of porcine circovirus-like viruses in pigs with porcine respiratory disease

Veterinary Microbiology, 2022
The emergence of the circular replication-associated protein (Rep) encoding single-stranded (CRESS) DNA viruses in different hosts has been associated with serious diseases, such as porcine diarrhea. The prevalence and pathogenicity of porcine circovirus-like virus (Po-Circo-like virus (PCLV)), a member of CRESS DNA virus, has not been fully ...
Xifeng, Hu, Zheng, Chen, Deping, Song, Yu, Li, Zhen, Ding, Xiangdong, Wu, Hongnan, You, Huansheng, Wu   +7 more
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Exogenous Porcine Viruses

2003
Porcine organs, cells and tissues provide a viable source of transplants in humans, though there is some concern of public health risk from adaptation of swine infectious agents in humans. Limited information is available on the public health risk of many exogenous swine viruses, and reliable and rapid diagnostic tests are available for only a few of ...
P S, Paul, P, Halbur, B, Janke, H, Joo, P, Nawagitgul, J, Singh, S, Sorden   +6 more
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In utero transmission of porcine torque teno viruses

Veterinary Microbiology, 2009
Sera and selected tissue homogenates collected from gnotobiotic swine never exposed to the environment or other swine tissues were tested for the presence of porcine torque teno virus (TTV) DNAs by nested and non-nested polymerase chain reactions (PCR) using primers specific for the untranslated region of porcine genogroups (g) 1 and 2. Twenty-three of
Tanja, Pozzuto, Bettina, Mueller, Brian, Meehan, Susan S, Ringler, Kathleen A, McIntosh, John A, Ellis, Annette, Mankertz, Steven, Krakowka   +7 more
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The structure of porcine parvovirus: comparison with related viruses

Journal of Molecular Biology, 2002
The structure of baculovirus-expressed porcine parvovirus (PPV) capsids was solved using X-ray crystallography and was found to be similar to the related canine parvovirus (CPV) and minute virus of mice (MVM). The PPV capsid protein has 57 % and 49 % amino acid sequence identity with CPV and MVM, respectively, but the degree of conservation of surface ...
Alan A, Simpson, Benoît, Hébert, Gail M, Sullivan, Colin R, Parrish, Zoltán, Zádori, Peter, Tijssen, Michael G, Rossmann   +6 more
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Biologic and immunologic properties of porcine type C viruses

Virology, 1975
Six different porcine cell lines spontaneously begin to release type C viruses after long-term propagation in vitro. Reverse transcriptases from all of the viral isolates are inhibited by immune IgG directed against the polymerase from the endogenous porcine type C virus PK(15).
M M, Lieber, C J, Sherr, R E, Benveniste, G J, Todaro   +3 more
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Simultaneous detection of three porcine viruses by multiplex PCR

Acta Veterinaria Hungarica, 2007
Specific oligonucleotide primers were selected and combined in a multiplex arrangement, in order to detect simultaneously three economically important porcine viruses by polymerase chain reaction (PCR). The pathogen panel was comprised of viruses that cause reproductive failure in infected herds: Aujeszky’s disease virus (ADV), porcine parvovirus (PPV)
Sámi, L., Ursu, Krisztina, McKillen, J., Kecskeméti, S., Belák, S., Kiss, I.   +5 more
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Advances in porcine gastroenteric viruses

2020
Trabajo presentado en VI International Veterinary Congress, celebrado en Sochi (Rusia), del 12 al 15 de abril de ...
Enjuanes Sánchez, Luis, Pascual-Iglesias, Alejandro, Sánchez, Carlos M., Zaberezhny, A, Solá Gurpegui, Isabel, Zúñiga Lucas, Sonia   +5 more
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