Results 131 to 140 of about 18,671,976 (307)
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Study on Applicability of Ball-and-Stick Model in Reservoir Pore-Throat Network Simulation
At present, the ball-and-stick model is widely used to simulate the reservoir pore-throat network. However, due to the large span of reservoir pore-throats, there is still a lack of effective verification on whether the ball-stick model is fully ...
Zhiyang Pan +6 more
core +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Data Curation Network Governance Model v 2, revised June 2022
, 2022 A revised version of the Data Curation Network's Governance Model for fiscal year 2022-2023 (July 1-June 30). This version of the DCN's Governance Model amends the description of the Executive Committee and it's roles and responsibilities as a DCN ...
Data Curation Network
core
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
FEBS Letters, EarlyView.Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley +1 more source
Pore Network Modeling of Tight Gas Formations
, 2015 Replicating pore topology/structure of tight gas reservoirs is essential for modeling fluid flow through such porous media. Constitutive relationships between the macroscopic properties of the medium can often help with such modeling efforts. This research demonstrates the validity of physically constructing a pore network for tight media based on ...
openaire +2 more sources
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
FEBS Letters, EarlyView.Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Experiment and Numerical Simulation of Effective Thermal Conductivity of Porous Media
工程科学与技术, 2011 :Effective thermal conductivity of porous media was investigated by experimental and numerical approaches. Fractal pore network model, which was the combination of fractal theory and pore network model, was used to research the effective thermal ...
doaj