Results 91 to 100 of about 8,129,869 (250)
Study on Flow in Fractured Porous Media Using Pore-Fracture Network Modeling
Microscopic flow in fractured porous media is a typical problem for the exploitation of tight reservoirs. The rapid-flow in the fractured porous-media is of great significance to efficient and continuous oil/gas exploitation.
Haijiao Liu +3 more
doaj +1 more source
Integrating computational fluid dynamic, artificial intelligence techniques, and pore network modeling to predict relative permeability of gas condensate. [PDF]
Zeinedini E, Dabir B, Dadvar M.
europepmc +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The Impacts of Surface Microchannels on the Transport Properties of Porous Fibrous Media Using Stochastic Pore Network Modeling. [PDF]
Huang X, Zhou W, Deng D, Liu B, Jiang K.
europepmc +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Effective Diffusion in Fibrous Porous Media: A Comparison Study between Lattice Boltzmann and Pore Network Modeling Methods. [PDF]
Huang X, Zhou W, Deng D.
europepmc +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
In geotechnical engineering, understanding the relationship between soil permeability and deformation is essential, particularly for applications like earth dams, where compaction‐induced permeability reduction is crucial for performance optimization. In
Rasoul Mirghafari +4 more
doaj +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source

