Results 41 to 50 of about 162,962 (266)
Geophysical Research Letters, 2017 Understanding the details of pressure migration during hydraulic stimulation is important for the design of an energy extraction system and reservoir management, as well as for the mitigation of hazardous‐induced seismicity.
Yusuke Mukuhira +4 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Journal of Marine Science and Engineering, 2019 Mat foundations are widely used in jack-up offshore platforms to support and transfer loads. Regarding mat foundations working on the seabed, the excess wave-induced pore pressure is critical to seabed stability, which may finally cause structural ...
Qingyun Yuan +2 more
doaj +1 more source
Journal of Rock Mechanics and Geotechnical Engineering, 2022 The accurate evaluation of pore pressure and injected volume is crucial for the laboratory characterization of hydromechanical responses of rock fractures. This study reports a series of laboratory experiments to systematically demonstrate the effects of
Yinlin Ji +3 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Yankuang ceshi, 2020 BACKGROUND The development potential of tight gas reservoirs of the Shanxi Formation in the southeastern Ordos Basin is huge. High-pressure mercury injection has been one of the most important methods for analyzing the pore-throat structure, however, it ...
ZHU Qing, QIAO Xiang-yang, ZHANG Lei
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Journal of Rock Mechanics and Geotechnical EngineeringPore pressure is a decisive measure to assess the reservoir’s geomechanical properties, ensures safe and efficient drilling operations, and optimizes reservoir characterization and production.
Muhsan Ehsan +8 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source