Results 61 to 70 of about 2,866,395 (294)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Pore Pressure Disturbance Induced by Multistage Hydraulic Fracturing in Shale Gas: Modelling and Field Application

Geofluids, 2019
Currently, there is no proper method to predict the pore pressure disturbance caused by multistage fracturing in shale gas, which has challenged drilling engineering in practice, especially for the infilling well drilling within/near the fractured zones.
Yijin Zeng, Zizhen Wang, Yanbin Zang, Ruihe Wang, Feifei Wang, Xinming Niu, Feng Niu   +6 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Pore fluid pressure detection within the plate boundary fault interface of the Costa Rica convergent margin using AVO attributes [PDF]

, 2013
textI conducted an amplitude vs. offset (AVO) analysis on newly acquired 3D seismic reflection data to detect elevated pore fluid content and pore fluid pressure along the Costa Rica convergent margin to address dewatering processes of subduction zone ...
Graf, Stephen Boyer
core  

Pore Water Pressure in Sand Bed under Oscillating Water Pressure [PDF]

, 1984
In this paper the theoretical method to analyse the pore water pressures in the sand bed under the oscillating water pressure is developed. In the former researchs the validity of the theoretical treatment for the one-dimensional problem has been ...
Maeno, Shiro, Nago, Hiroshi
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Experimental Study on the Distribution of Wave-Induced Excess Pore Pressure in a Sandy Seabed around a Mat Foundation

Journal of Marine Science and Engineering, 2019
Mat foundations are widely used in jack-up offshore platforms to support and transfer loads. Regarding mat foundations working on the seabed, the excess wave-induced pore pressure is critical to seabed stability, which may finally cause structural ...
Qingyun Yuan, Chencong Liao, Xianglian Zhou   +2 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Pore pressure prediction based on conventional well logs and seismic data using an advanced machine learning approach

Journal of Rock Mechanics and Geotechnical Engineering
Pore pressure is a decisive measure to assess the reservoir’s geomechanical properties, ensures safe and efficient drilling operations, and optimizes reservoir characterization and production.
Muhsan Ehsan, Umar Manzoor, Rujun Chen, Muyyassar Hussain, Kamal Abdelrahman, Ahmed E. Radwan, Jar Ullah, Muhammad Khizer Iftikhar, Farooq Arshad   +8 more
doaj   +1 more source