Results 81 to 90 of about 207,601 (314)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Numerical investigation of solute migration and release from sediments driven by wave-induced accumulation of pore water pressure

open access: yes, 2023
Sediments with poor drainage conditions are prone to build-up of excess pore water pressure when exposed to dynamic wave loading. This results in accumulated seepage flow that may have a significant impact on migration of solutes in marine sediments.
Liu, X   +11 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Pore scale modeling of capillary pressure curves in 2D rock images [PDF]

open access: yes, 2013
Capillary pressure is relevant to most processes of multiphase flow inporous media, as it controls the pore scale fluids distribution. Reliable capillary pressure curves are required to model and predict larger-scale multiphase flow processes; normally ...
Zhou, Yingfang
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Elasto-plasticity and pore-pressure coupled analysis on the pullout behaviors of a plate anchor

open access: yes, 2015
A numerical method is proposed for the elasto-plasticity and pore-pressure coupled analysis on the pullout behaviors of a plate anchor. The bounding-surface plasticity (BSP) model combined with Biot's consolidation theory is employed to simulate the ...
Hu C(胡存), Gao FP(高福平)
core   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Some experience in measuring pore water suction in Dublin glacial till

open access: yes, 2004
Several recent articles and discussions in GIN, by Penman (2002), Thomann et al. (2003), Ridley (2003) and Sellers et al. (2003) highlight the importance of pore water pressure and suctions and in particular the difficulties associated with measuring ...
Long, Michael (Michael M.)   +2 more
core  

(Table 2) Pore fluid pressure at DSDP Leg 84 Sites

open access: yes, 1985
(Table 2) Pore fluid pressure at DSDP Leg 84 ...
von Huene, Roland   +1 more
core   +1 more source

Development law and growth model of dynamic pore water pressure of tailings under different consolidation conditions

open access: yesPLoS ONE, 2022
Tailings dams are in danger of liquefaction during earthquakes. The liquefaction process can be indirectly reflected by the evolution rule of the dynamic pore water pressure.
Changbo Du   +4 more
doaj  

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