Results 81 to 90 of about 2,866,395 (294)

Pore pressure estimation from single and repeated seismic data sets [PDF]

open access: yes, 2005
Høye poretrykk utgjør en risiko for boreoperasjoner på Norsk Sokkel og internasjonalt. Denne risikoen kan reduseres dersom man har kjennskap til poretrykksforholdene før boring.
Kvam, Øyvind
core  

What have we learned from two-pore potassium channels? Their molecular configuration and function in the human heart [PDF]

open access: yes, 2012
Two-pore domain potassium channels (K2P) control excitability, stabilize the resting membrane potential below firing threshold, and accelerate repolarisation in different cells.
Szalontai, B.   +23 more
core   +2 more sources

Development law and growth model of dynamic pore water pressure of tailings under different consolidation conditions

open access: yesPLoS ONE, 2022
Tailings dams are in danger of liquefaction during earthquakes. The liquefaction process can be indirectly reflected by the evolution rule of the dynamic pore water pressure.
Changbo Du   +4 more
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

An experimental study on variation of pore pressure and wave velocity in carbonate rocks: impact of depositional facies and diagenesis

open access: yesGeomechanics and Geophysics for Geo-Energy and Geo-Resources
Over the years, the observation of wave velocity in relation to pore pressure variation has emerged as an intriguing topic in reservoir characterization. Considering the significant role of geological deposition processes (e.g., diagenesis and facies) on
Javad Sharifi   +3 more
doaj   +1 more source

Influence of pore pressure and production-induced changes in pore pressure on in situ stress [PDF]

open access: yes, 1996
Knowledge of in situ stress and how stress changes with reservoir depletion and pore pressure drawdown is important in a multi-disciplinary approach to reservoir characterization, reservoir management, and improved oil recovery projects. This report summarizes a compilation of in situ stress data from six fields showing the effects of pore pressure and
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Wave-induced Pore Pressure Responses and Soil Liquefaction Around Pile Foundation

open access: yes, 2011
A 3D FEM model is proposed and verified with existing experimental data for simulating wave-induced transient and residual pore pressure responses around a pile foundation.
杨兵, Zang J, 高福平, 李小均
core   +2 more sources

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