Results 91 to 100 of about 2,866,395 (294)

Estimating of Pore Pressure Gradient in Lower Fars Formation

Iraqi Journal of Chemical and Petroleum Engineering, 2018
In petroleum industry, the early knowledge of “pore pressure gradient” is the basis in well design and the extraction of these information is more direct when the pore pressure gradient is equal to normal gradient; however, this matter will be more ...
Neaam F. Hussain, Faleh H. M. Al Mahdawi
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Pore pressure prediction using seismic velocity modeling: case study, Sefid-Zakhor gas field in Southern Iran

Journal of Petroleum Exploration and Production Technology, 2019
Pore pressure estimation is important for both exploration and drilling projects. During the exploration phase, a prediction of pore pressure can be used to evaluate exploration risk factors including the migration of formation fluids and seal integrity.
Zahra Bahmaei, Erfan Hosseini
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Study on dynamic characteristics of saturated loess with liquefied flow-slide induced by Jishishan earthquake in Zhongchuan, Qinghai Province

Yantu gongcheng xuebao
The 2023 Jishishan Mw6.2 earthquake induced the liquefaction flow slip of loess in Zhongchuan Township. In order to reveal its low-angle long-distance slip mechanism, based on the dynamic triaxial tests and microstructure analysis of undisturbed ...
JIA Shichao 1, ZHONG Xiumei 2, WANG Qian 2, WANG Yi 1, WANG Yan 2, HU Xuefeng 2
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

A coupled mathematical model for accumulation of wave-induced pore water pressure and its application

, 2019
Prediction of the wave-induced instability of seabed due to the build-up of pore water pressure is essential for coastal engineers involved in the foundation design of marine infrastructure.
Cui, HN, Jeng, DS, Zhao, HY, Liu, XL
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Elasto-plasticity and pore-pressure coupled analysis on the pullout behaviors of a plate anchor

, 2015
A numerical method is proposed for the elasto-plasticity and pore-pressure coupled analysis on the pullout behaviors of a plate anchor. The bounding-surface plasticity (BSP) model combined with Biot's consolidation theory is employed to simulate the ...
Hu C(胡存), Gao FP(高福平)
core   +1 more source