Results 91 to 100 of about 522,196 (302)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Two-phase, passive separator-and-filter assembly [PDF]

open access: yes, 1974
Assembly separates liquid from gas by passive hydrophilic/hydrophobic material approach. Apparatus is comprised of porous glass hydrophilic tubes. Quantity, lateral size, and pore size of glass tubes are determined by particular design requirements with ...
Erickson, A. C., Porter, F. J., Jr.
core   +1 more source

A Model for Tracking Fronts of Stress-Induced Permeability Enhancement

open access: yes, 2013
Using an analogy to the classical Stefan problem, we construct evolution equations for the fluid pore pressure on both sides of a propagating stress-induced damage front.
Karra, Satish   +2 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Development law and growth model of dynamic pore water pressure of tailings under different consolidation conditions

open access: yesPLoS ONE, 2022
Tailings dams are in danger of liquefaction during earthquakes. The liquefaction process can be indirectly reflected by the evolution rule of the dynamic pore water pressure.
Changbo Du   +4 more
doaj  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Revealing the pure confinement effect in glass-forming liquids by dynamic mechanical analysis

open access: yes, 2010
Many molecular glass forming liquids show a shift of the glass transition Tg to lower temperatures when the liquid is confined into mesoporous host matrices.
F. Rouguerol   +5 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An experimental study on variation of pore pressure and wave velocity in carbonate rocks: impact of depositional facies and diagenesis

open access: yesGeomechanics and Geophysics for Geo-Energy and Geo-Resources
Over the years, the observation of wave velocity in relation to pore pressure variation has emerged as an intriguing topic in reservoir characterization. Considering the significant role of geological deposition processes (e.g., diagenesis and facies) on
Javad Sharifi   +3 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Home - About - Disclaimer - Privacy