Results 91 to 100 of about 522,196 (302)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Two-phase, passive separator-and-filter assembly [PDF]
Assembly separates liquid from gas by passive hydrophilic/hydrophobic material approach. Apparatus is comprised of porous glass hydrophilic tubes. Quantity, lateral size, and pore size of glass tubes are determined by particular design requirements with ...
Erickson, A. C., Porter, F. J., Jr.
core +1 more source
A Model for Tracking Fronts of Stress-Induced Permeability Enhancement
Using an analogy to the classical Stefan problem, we construct evolution equations for the fluid pore pressure on both sides of a propagating stress-induced damage front.
Karra, Satish +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Tailings dams are in danger of liquefaction during earthquakes. The liquefaction process can be indirectly reflected by the evolution rule of the dynamic pore water pressure.
Changbo Du +4 more
doaj
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Revealing the pure confinement effect in glass-forming liquids by dynamic mechanical analysis
Many molecular glass forming liquids show a shift of the glass transition Tg to lower temperatures when the liquid is confined into mesoporous host matrices.
F. Rouguerol +5 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Over the years, the observation of wave velocity in relation to pore pressure variation has emerged as an intriguing topic in reservoir characterization. Considering the significant role of geological deposition processes (e.g., diagenesis and facies) on
Javad Sharifi +3 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

