Results 101 to 110 of about 522,196 (302)
Pore pressure estimation is important for both exploration and drilling projects. During the exploration phase, a prediction of pore pressure can be used to evaluate exploration risk factors including the migration of formation fluids and seal integrity.
Zahra Bahmaei, Erfan Hosseini
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Estimating of Pore Pressure Gradient in Lower Fars Formation
In petroleum industry, the early knowledge of “pore pressure gradient” is the basis in well design and the extraction of these information is more direct when the pore pressure gradient is equal to normal gradient; however, this matter will be more ...
Neaam F. Hussain, Faleh H. M. Al Mahdawi
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Hydrogen storage in nickel doped MCM-41 [PDF]
Hydrogen as an energy carrier is one of the best environmentally friendly alternatives to fossil fuel sources. The potential use of hydrogen results with increasing demand to hydrogen production and storage. Recent studies show that materials having high
Dundar Tekkaya, Ezgi +3 more
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Soil pipes are commonly found in landslide scarps, and it has been suggested that build-up of pore water pressure due to clogged soil pipes influences landslide initiation.
Yasutaka Tanaka +3 more
doaj +1 more source

