Derivation, validation, and prediction of loading-induced mineral apposition rates at endocortical and periosteal bone surfaces based on fluid velocity and pore pressure. [PDF]
Singh S, Singh SJ, Prasad J.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Soil consolidation acoustic experiment and pore pressure prediction model establishment-taking the Yingqiong Basin as an example. [PDF]
Han Z, Sun B, Cheng Y, Yan C.
europepmc +1 more source
The Mechanical Coupling of Fluid-Filled Granular Material Under Shear [PDF]
The coupled mechanics of fluid-filled granular media controls the physics of many Earth systems, for example saturated soils, fault gouge, and landslide shear zones.
Aharonov, E. +3 more
core
We present gravimetrical, optical, and neutron imaging measurements of the capillarity-driven infiltration of mesoporous silica glass by hydrocarbons. Square-root-of-time Lucas-Washburn invasion kinetics are found for linear alkanes from n-decane (C10 ...
Egelhaaf, Stefan U. +4 more
core +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Development of Pore Pressure in Cementitious Materials under Low Thermal Effects: Evidence from Optimization of Pore Structure by Incorporation of Fly Ash. [PDF]
Jiang W, Zhang D, Zheng X, Li W.
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Effects of an impermeable layer on pore pressure response to tsunami-like inundation. [PDF]
Exton M, Yeh H.
europepmc +1 more source
A Simple Model to Predicting Pore Pressure from Shear Wave Sensitivity Analysis [PDF]
A successful seismicity alongside core analysis provides data for subsurface structural mapping, definition of lithology, identification of the productive zones, description of their depths and thickness.
Enaworu, E. +3 more
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