Results 141 to 150 of about 834,609 (355)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

CTAB on Synthesis and Pore Structure of Hierarchical Zeolite

open access: diamond, 2018
Hongji Li   +5 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Characterization of Dolomite Reservoir Pore‐Throat Structure Based on Cast Thin Section Image Analysis and Fractal Theory: A Case Study of Middle Jurassic Dolomite in the Southern Depression of Qiangtang Basin, Northern Tibetan Plateau, China

open access: yesEnergy Science & Engineering
The Middle Jurassic Buqu Formation dolomite in the Qiangtang Basin, northern Tibetan Plateau, is characterized by strong heterogeneity, low porosity, and low permeability, making the evaluation of its pore structure a challenging task.
Zhonglin Wang   +4 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile [PDF]

open access: gold, 2022
Akihiro Kawamoto   +5 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Heterogeneity and permeability estimation of pore-throat structure at different scales in deep tight sandstone reservoirs: A case study of Paleogene Hetaoyuan Formation in Anpeng area, Nanxiang Basin, China.

open access: yesPLoS ONE
Clarifying the pore-throat size and pore size distribution of tight sandstone reservoirs, quantitatively characterizing the heterogeneity of pore-throat structures, is crucial for evaluating reservoir effectiveness and predicting productivity.
Yan Zhu   +5 more
doaj   +1 more source

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