Results 161 to 170 of about 834,609 (355)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Pore Structure Analysis of various water-binder ratios Ternary blended Concrete made with [PDF]

, 2020
D Adinarayana, P. Srinivasa Rao, V Srinivasa Reddy   +2 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

The role of pore structure on char reactivity. Quarterly progress report

, 1992
A.F. Sarofim
openalex   +2 more sources

The Structure of a Melittin Stabilized Toroidal Pore [PDF]

, 2015
John M. Leveritt
openalex   +1 more source

Fabrication of aerogel scaffolds with adjustable macro/micro-pore structure through 3D printing and sacrificial template method for tissue engineering

, 2022
Zhichao Wang, Chuanzhen Huang, Xu Han, Shuying Li, Zhen Wang, Jun Huang, Hanlian Liu, Zhuang Chen   +7 more
openalex   +1 more source

Do Pores Exist?—Foundational Issues in Pore Structural Characterisation

Foundations
This work reviews a range of fundamental theoretical considerations in pore structural characterisation. The pore concept is essential for providing a better understanding of physical processes arising within porous media than purely phenomenological approaches.
openaire   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Fine structure and function of the genital pore of the female of Intoshia variabili (Orthonectida) [PDF]

, 2004
George S. Slyusarev
openalex   +1 more source

Novel Pd-loaded self-standing hierarchical pore structure silicalite for low temperature toluene catalytic combustion [PDF]

, 2022
Kang Deng, Liangjun Xiao, Junming Xie, Shunheng Tu, Yongfeng Li   +4 more
openalex   +1 more source