Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
Dynamic Characterization of Microscopic Pore Structure in Medium-High Permeability Sandstones During Waterflooding. [PDF]
Wu J+7 more
europepmc +1 more source
Thermodynamics of Formation of Porous Polymeric Membrane by Phase Separation Method V. Probabilities of Finding Through-, Semi-Open, and Isolated Pores in Three-Dimensional Membrane Structure Model Constructed by Computer Simulation Experiment [PDF]
Hideki Iijima+2 more
openalex +1 more source
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova+26 more
wiley +1 more source
Structure–function studies of tryptophan mutants of equinatoxin II, a sea anemone pore-forming protein [PDF]
Petra Malovrh+5 more
openalex +2 more sources
Pore structure and reactivity changes in hot coal gas desulfurization sorbents
Stratis V. Sotirchos
openalex +2 more sources
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza+5 more
wiley +1 more source
A rationally thin composite membrane with differentiated pore structure for industrial-scale alkaline water electrolysis. [PDF]
You J+13 more
europepmc +1 more source
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha+10 more
wiley +1 more source