Results 61 to 70 of about 7,332 (179)

Mechanisms of Gui Zhi Fu Ling Formula in Liver Fibrosis: Metabolomics and Gut Microbiota Analysis

open access: yeseFood, Volume 7, Issue 3, June 2026.
Our study was based on the efficacy of the phenotype in an animal model and used multi‐omics to explore the mechanism of action of the compound. We found that Gui Zhi Fu Ling Formula may ameliorate hepatic fibrosis potentially associated with increased hepatic EPA and the expression of gut Pseudomonas.
Xiaoliang Deng   +5 more
wiley   +1 more source

RNA-protein UV-crosslinking Assay

open access: yesBio-Protocol, 2017
RNA-protein interactions play a crucial role in every aspect of RNA metabolism, and also plays a major role in post-transcriptional gene regulation.
Dipak Poria, Partho Ray
doaj   +1 more source

Polyphenol‐Rich Duhuo Jisheng Decoction Enhances Mesenchymal Stem Cell–Derived Exosome–Mediated Chondroprotection via PI3K/AKT Signaling in Osteoarthritis

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
This graphical abstract illustrates the chondroprotective mechanism of exosomes derived from bone marrow mesenchymal stem cells (BMSCs) preconditioned with polyphenol‐rich Duhuo Jisheng Decoction (DHJST‐Exos). Enriched with bioactive compounds such as wogonin, quercetin, and kaempferol, DHJST‐Exos effectively ameliorate osteoarthritis (OA ...
Zhouwei Liao   +9 more
wiley   +1 more source

Food and Medicine Homologous Plants in Osteoporosis: A Scoping Review of Preclinical Evidence

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
Food and medicine homologous (FMH) plants and their bioactive compounds exhibit potential osteoprotective effects through multiple complementary mechanisms, including estrogen‐like signaling, attenuation of oxidative stress, modulation of the gut microbiota–bone axis, and regulation of autophagy.
Long Zhao   +4 more
wiley   +1 more source

Formulation and Pharmacological Evaluation of a Medicine‐Food Homology Herb‐Based Formula for Sleep Enhancement

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
This outlines the progress for developing a sleep‐modulating herbal formula (SMF). It begins with the identification of effective compounds and quality control, then uses network pharmacology and molecular docking to explain the mechanisms behind the observation found on the behavioural and neurobiological results in animal study.
Jasmine U. Ting   +7 more
wiley   +1 more source

Progress in the study of bioactivity, chemical composition and pharmacological mechanism of action in Wolfiporia cocos (F.A. Wolf) Ryvarden & Gilb

open access: yesFrontiers in Pharmacology
The Latin name of Wolfiporia cocos is Wolfiporia cocos (F.A. Wolf) Ryvarden & Gilb, it a medicinal and edible mushroom belonging to the family Polyporaceae.
Qi Xiong   +9 more
doaj   +1 more source

In vitro colonic fermentation of fermented Radix Astragali by Poria cocos and anti-hyperuricemia mechanism based on network pharmacology and experiment verification

open access: yesFrontiers in Nutrition
AimThis research aimed to probe the effects of fecal microbiota and Lactobacillus acidophilus on the metabolism of Radix Astragali (RA) and Poria cocos solid fermenting Radix Astragali (FRA). It further explores pharmacological effects of RA, Poria cocos,
Caiyun Chen   +10 more
doaj   +1 more source

Data mining on the medication rules of Chinese medicine for diabetic nephropathy

open access: yesZhongguo linchuang yanjiu
Objective To investigate the medication patterns of Chinese medicine in treating diabetic nephronpathy through data mining analysis. Methods A comprehensive collection of medical prescriptions for Chinese medicine treatment of diabetic nephropathy was ...
ZOU Xunxia   +4 more
doaj   +1 more source

Chaetochromones A and B, Two New Polyketides from the Fungus Chaetomium indicum (CBS.860.68)

open access: yesMolecules, 2013
Chaetochromones A (1) and B (2), two novel polyketides, were isolated from the crude extract of fungus Chaetomium indicum (CBS.860.68) together with three known analogues PI-3(3), PI-4 (4) and SB236050 (5).
Xuewei Wang   +4 more
doaj   +1 more source

Light and the City: Breast Cancer Risk Factors Differ Between Urban and Rural Women in Israel

open access: yesIntegrative Cancer Therapies, 2017
Women are exposed to indoor and outdoor artificial light at night (ALAN) in urban and rural environments. Excessive exposure to hazardous ALAN containing short wavelength light may suppress pineal melatonin production and lead to an increased breast ...
Atalya Keshet-Sitton MSc   +4 more
doaj   +1 more source

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