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A formulation of combined <i>Poria cocos</i> and <i>Cordyceps militaris</i> rice ameliorates depressive-like effects by downregulating p38 MAPK signaling pathways. [PDF]

J Tradit Complement Med
Huang YJ, Wu HY, Chang WT, Lu KH, Lin YE, Huang HS, Lu YS, Sheen LY.   +7 more
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Carboxymethylated β-Glucan Derived from Poria cocos with Biological Activities

Journal of Agricultural and Food Chemistry, 2009
Water-insoluble beta-(1-3)-D-glucan isolated from the sclerotium of Poria cocos hardly exhibits biological activity. Therefore, it is advantageous to produce a value-added product from P. cocos. We extracted the beta-(1-3)-D-glucan from the sclerotium of P. cocos and synthesized a carboxymethylated derivative.
Yongjiang, Wang, Yuanzhi, Yu, Jianwei, Mao   +2 more
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Poria cocos: traditional uses, triterpenoid components and their renoprotective pharmacology

Acta Pharmacologica Sinica
Poria cocos and its surface layer of Poria cocos (Schw.) Wolf (Polyporaceae), are used in traditional Chinese medicine for its diuretic and renoprotective effects. Phytochemical studies have shown that lanostane and 3,4-seco-lanostane tetracyclic triterpenoids are the main components of P. cocos and its surface layer.
Zhi-Yuan, Guo, Xin, Wu, Shui-Juan, Zhang, Jian-Hua, Yang, Hua, Miao, Ying-Yong, Zhao   +5 more
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Chemical constituents of Poria cocos

China Journal of Chinese Materia Medica, 2014
The chemical constituents of Poria cocos were studied by means of silica gel, ODS column chromatography, Sephadex LH-20 and preparative HPLC. Thirteen compounds were isolated from this plant. By analysis of the ESI-MS and NMR data, the structures of these compounds were determined as tumulosic acid (1), dehydrotumulosic acid (2), 3beta, 5alpha ...
Peng-Fei, Yang, Chao, Liu, Hong-Qing, Wang, Jia-Chun, Li, Zhen-Zhong, Wang, Wei, Xiao, Ruo-Yun, Chen   +6 more
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Triterpenes of Poria cocos

Phytochemistry, 1993
Abstract Four lanostane triterpenes and four novel 3,4- seco -lanostane triterpenes were isolated from the surface layer of Poria cocos . 3β-Hydroxylanosta-7,9(11),24-trien-21-oic acid, trametenolic acid, dehydroeburicoic acid and eburicoic acid were isolated by HPLC after treatment with N -chloromethylphthalimide. Four novel 3,4- seco -lanostanes:
Takaaki Tai, Akira Akahori, Tetsuro Shingu   +2 more
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Cytotoxic Lanostanoids from Poria cocos

Journal of Natural Products, 2016
Six new and 16 known lanostanoids were isolated from the sclerotia of Poria cocos. The structures of the new isolates were elucidated to be 16α-hydroxy-3-oxo-24-methyllanosta-5,7,9(11),24(31)-tetraen-21-oic acid (1), 3β,16α,29-trihydroxy-24-methyllanosta-7,9(11),24(31)-trien-21-oic acid (2), 3β,16α,30-trihydroxy-24-methyllanosta-7,9(11),24(31)-trien-21-
Kuei-Hung, Lai, Mei-Chin, Lu, Ying-Chi, Du, Mohamed, El-Shazly, Tung-Ying, Wu, Yu-Ming, Hsu, Astrid, Henz, Juan-Cheng, Yang, Anders, Backlund, Fang-Rong, Chang, Yang-Chang, Wu   +10 more
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Triterpenoids from Poria cocos

Phytochemistry, 1991
Abstract Two new triterpenoids, poricoic acid A and B were isolated from the surface layer of Poria cocos . The structures of poricoic acid A and B were elucidated to be 16α-hyroxy-3,4-secolanosta-4(28),7,9(11),24(31)-tetraen-3,21-dioic acid, and 16α-hydroxy-3,4-secolanosta-4(28),7,9(11),24-tetraen-3,21-dioic acid, respectively.
Takaaki Tai, Akira Akahori, Tetsuro Shingu   +2 more
openaire   +1 more source

Anti-Emetic Principles ofPoria cocos

Planta Medica, 1995
The triterpenes isolated from P. cocos and their derivatives were examined for anti-emetic activity. Some of these triterpenes inhibited emetic action induced by oral administration of copper sulfate pentahydrate to leopard frog. The triterpenes having an exomethylene group at C-24 showed anti-emetic activity to frogs.
T, Tai, Y, Akita, K, Kinoshita, K, Koyama, K, Takahashi, K, Watanabe   +5 more
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A lanostane triterpenoid from Poria cocos

Phytochemistry, 1992
Abstract The dehydro derivative of pachymic acid was isolated from the sclerotium of Poria cocos . Its structure has been shown to be 3β-acetyloxy-16α-hydroxylanosta-7,9(11), 24(31)-trien-21-oic acid.
Tetsuro Shingu, Takaaki Tai, Akira Akahori   +2 more
openaire   +1 more source