Results 41 to 50 of about 189,015 (256)

A Numerical Study on Aircraft Noise Mitigation Using Porous Stator Concepts

Aerospace, 2022
This manuscript presents the application of a recently developed noise reduction technology, constituted by poro-serrated stator blades on a full-scale aircraft model, in order to reduce rotor-stator interaction noise in the fan stage.
Christopher Teruna, Leandro Rego, Damiano Casalino, Daniele Ragni, Francesco Avallone   +4 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Numerical Equivalent Acoustic Material for Air-Filled Porous Absorption Simulations in Finite Different Time Domain Methods: Design and Comparison

Applied Sciences
Extracting the microscopic parameters of a porous material is a complex task, and attempts have been made to develop models that can simulate their characteristics, gathering the least amount of information possible. As a case in point, tests to evaluate
P. C. Iglesias, L. Godinho, J. Redondo
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Tissue engineering scaffold material of porous nanohydroxyapatite/polyamide 66

International Journal of Nanomedicine, 2010
Qian Xu1, Hongyan Lu1, Jingchao Zhang1, Guoyu Lu2, Zhennan Deng2, Anchun Mo31State Key Laboratory of Oral Diseases, Sichuan University, Chengdu, 610041, P.R. China; 2Research Center for Nano-Biomaterials, Sichuan University, Chengdu, 610064, P.R.
Qian Xu, Hongyan Lu, Jingchao Zhang, et al   +3 more
doaj  

Parametric modeling and simulation analysis of porous materials prepared by 3D printing technology

International Journal for Simulation and Multidisciplinary Design Optimization
The study in this paper is the modeling as well as simulation analysis of porous materials prepared by 3D printing technique. The structural simulation analysis of porous material is carried out using ANSYS Workbench 15.0 to derive the deformation as ...
Li Tianhua, Ma Hailong, Xu Shubo, Liu Renhui, Pan Yuefei, Ren Guocheng, Li Jianing, Zhao Zhongkui   +7 more
doaj   +1 more source

Porous Materials Derived from Industrial By-Products for Titanium Dioxide Nanoparticles Capture

Applied Sciences, 2020
The aim of this paper was the evaluation of hybrid porous materials, named SUNSPACE (“SUstaiNable materials Synthesized from by-Products and Alginates for Clean air and better Environment”), realized with raw materials such as silica fume (SUNSPACE SF ...
Antonella Cornelio, Alessandra Zanoletti, Stefania Federici, Laura Eleonora Depero, Elza Bontempi   +4 more
doaj   +1 more source