Results 51 to 60 of about 189,015 (256)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Review on Synthesis Method, Classification and AdsorptionSeparation and Sensing Application of Metal-Organic Frameworks (MOFs) Based Composites [PDF]

open access: yesJournal of Water and Environmental Nanotechnology
A group of supramolecular solid materials known as "metal organic frameworks"(MOFs) are a type of hybrid networks made up of a variety of inorganic and organic linkers that are all tightly bonded to metal ions.
Aklilu Melese   +4 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Characteristics of Oxide Films on Zr702 and Their Corrosion Performance in Boiling Fluorinated Nitric Acid

open access: yesMetals
Fluoride ions, which interfere with the oxide formation on zirconium have been over-looked until recently. The effect of fluoride ions on oxide formation and dissolution behaviors in zirconium was investigated in this study.
Hangbiao Su   +4 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Response of porous SMA: a micromechanical study

open access: yesFracture and Structural Integrity, 2014
Lately porous shape memory alloys (SMA) have attracted great interest as low weight materials characterized by high energy dissipation capability. In the present contribution a micromechanical study of porous SMA is proposed, introducing the simplifying ...
V. Sepe, S. Marfia, F. Auricchio
doaj  

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Femtosecond Laser Microfabrication of Porous Superwetting Materials for Oil/Water Separation: A Mini-Review

open access: yesFrontiers in Chemistry, 2020
Frequent oil-leakage accidents and large quantities of oil-bearing wastewater discharge cause severe environmental pollution and huge economic losses. Recently, superwetting porous materials are successfully utilized to separate oil/water mixture (OWM ...
Na Feng, Jiale Yong
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

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