Results 41 to 50 of about 400,325 (291)
Pore-scale numerical simulation of supercritical CO2-brine two-phase flow based on VOF method
CO2 capture and storage technology is favorable for the reduction of CO2 emissions. In recent years, a great number of research achievements have been obtained on CO2 geological storage from nano scale to oil/gas reservoir scale, but most studies only ...
Yongfei Yang +4 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Transient flows in active porous media [PDF]
Stimuli-responsive materials that modify their shape in response to changes in environmental conditions -- such as solute concentration, temperature, pH, and stress -- are widespread in nature and technology.
Jensen, Kaare H., Kosmidis, Lefteris I.
core +2 more sources
Homogenization of two fluid flow in porous media
The macroscopic behavior of air and water in porous media is often approximated using Richards’ equation for the fluid saturation and pressure. This equation is parametrized by the hydraulic conductivity and water release curve.
Daly, K. R., Roose, T.
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
In porous water filters, the transport and entrapment of contaminants can be modeled as a classic mass transport problem, which employs the conventional convection–dispersion equation to predict the transport of species existing in trace amounts.
Parham Mobadersani +2 more
doaj +1 more source
Rhodolith beds built by free-living coralline algae are important ecosystems for marine biodiversity and carbonate production. Yet, our mechanistic understanding regarding rhodolith physiology and its drivers is still limited.
Nadine Schubert +8 more
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Gas condensate reservoirs usually exhibit complex flow behaviors because of propagation response of pressure drop from the wellbore into the reservoir.
Shams Bilal +3 more
doaj +1 more source
In Situ Deformation Analysis of a Fracture in Coal under Cyclic Loading and Unloading
The deformation analysis of fractures is vital for advantageous development of oil and gas fields, especially the coalbed methane (CBM) reservoir, since the change of fracture parameters can be directly evaluated through fracture deformation analysis ...
Zhihui Liu +3 more
doaj +1 more source

