Results 41 to 50 of about 139,632 (315)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

The transport behaviour of elemental mercury DNAPL in saturated porous media: Analysis of field observations and two-phase flow modelling

, 2014
Mercury is a contaminant of global concern. The use of elemental mercury in various (former) industrial processes, such as chlorine production at chlor-alkali plants, is known to have resulted in soil and groundwater contaminations worldwide.
Hydrogeology, Marsman, A., Keijzer, T.J.S., Sweijen, T., NWO-STW: Interfacial aspects of ionized porous media, Hartog, Niels   +5 more
core   +1 more source

Microfluidic systems for the analysis of the viscoelastic fluid flow phenomena in porous media [PDF]

, 2011
In this study, two microfluidic devices are proposed as simplified 1-D microfluidic analogues of a porous medium. The objectives are twofold: firstly to assess the usefulness of the microchannels to mimic the porous medium in a controlled and simplified ...
P. J. Hamersma, Pinho, F.T. (author), Galindo-Rosales, Francisco J, Oliveira, M.S.N., E. van Bokhorst, Hamersma, P.J., Campo-Deaño, L., Fernando T. Pinho, F. T. Pinho, Francisco J. Galindo Rosales, Laura Campo Deaño, Hamersma, P.J. (author), Galindo-Rosales, F.J., Manuel A. Alves, Campo-Deaño, Laura, M. A. Alves, Oliveira, M. S. N., L. Campo-Deaño, Galindo-Rosales, F. J., M. S. N. Oliveira, Alves, M.A. (author), Mónica S. N. Oliveira, Oliveira, M.S.N. (author), F. J. Galindo-Rosales, Oliveira, Monica, Alves, M.A., Van Bokhorst, E. (author), Campo-Deano, L. (author), Pinho, F.T., van Bokhorst, E., Galindo-Rosales, F.J. (author)   +30 more
core   +1 more source

Evaluation of a Volume-Averaged Species Transport Model with Micro–Macro Coupling for Breakthrough Curve Prediction

Molecules
In porous water filters, the transport and entrapment of contaminants can be modeled as a classic mass transport problem, which employs the conventional convection–dispersion equation to predict the transport of species existing in trace amounts.
Parham Mobadersani, Naine Tarun Bharat, Krishna M. Pillai   +2 more
doaj   +1 more source

Pore-scale numerical simulation of supercritical CO2-brine two-phase flow based on VOF method

Natural Gas Industry B, 2023
CO2 capture and storage technology is favorable for the reduction of CO2 emissions. In recent years, a great number of research achievements have been obtained on CO2 geological storage from nano scale to oil/gas reservoir scale, but most studies only ...
Yongfei Yang, Jinlei Wang, Jianzhong Wang, Qi Zhang, Jun Yao   +4 more
doaj   +1 more source

Reactive Transport in Porous Media [PDF]

ESAIM: Proceedings, 2009
Nous présentons une méthode numérique pour le couplage du transport et de la chimie en milieu poreux. Notre méthode utilise un algorithme de point fixe, qui nous permet de coupler des modules de transport et de chimie différents. Nous présentons les méthodes numériques utilisées pour chacun des sous-problèmes, ainsi qu'une formulation pour le problème ...
Apoung-Kamga, Jean-Baptiste, Have, Pascal, Houot, Jean, Kern, Michel, Semin, Adrien   +4 more
openaire   +3 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Convection in fluid and porous media [PDF]

, 2003
The subject of convection in fluid and porous media is investigated. Particular attention is paid to penetrative convection. The first two chapters are devoted to penetrative convection when fluid overlies and saturates a porous medium.
Carr, Magda
core  

Sensitivity analysis and economic optimization studies of inverted five-spot gas cycling in gas condensate reservoir

Open Physics, 2017
Gas condensate reservoirs usually exhibit complex flow behaviors because of propagation response of pressure drop from the wellbore into the reservoir.
Shams Bilal, Yao Jun, Zhang Kai, Zhang Lei   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source