Results 61 to 70 of about 7,354,629 (287)

Porous Scaffold Design for Additive Manufacturing in Orthopedics: A Review

Frontiers in Bioengineering and Biotechnology, 2020
With the increasing application of orthopedic scaffolds, a dramatically increasing number of requirements for scaffolds are precise. The porous structure has been a fundamental design in the bone tissue engineering or orthopedic clinics because of its ...
Hao Chen, Qing Han, Chenyu Wang, Yang Liu, Bingpeng Chen, Jincheng Wang   +5 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

The performance of a porous ceramic hydrostatic journal bearing [PDF]

, 2010
The performance of a porous-ceramic hydrostatic journal bearing manufactured by the starch consolidation (SC) technique has been examined using a highly instrumented test rig.
Corbett, John, Durazo-Cardenas, Isidro, Stephenson, David J.   +2 more
core   +1 more source

Quasi‐Periodic Porous Structures‐Based Temperature and Pressure Dual‐Mode Electronic Skin for Material Cognition

Advanced Science
It is of great significance to prepare a temperature and pressure (T‐P) dual‐mode electronic skin (DMES) with a controllable porous structure and use it to achieve material cognition.
Xiaoguang Gao, Chengzhen Xue, Xiaoliang Zhang, Xuejuan Meng, Xiaochun Li, Li Niu   +5 more
doaj   +1 more source

Preparation, Characterization and Properties of Porous PLA/PEG/Curcumin Composite Nanofibers for Antibacterial Application

Nanomaterials, 2019
Polylactide/polyethylene glycol/curcumin (PLA/PEG/Cur) composite nanofibers (CNFs) with varying ratios of PEG were successfully fabricated by electrospinning.
Feifei Wang, Zhaoyang Sun, Jing Yin, Lan Xu   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Effect of topological configuration on mechanical properties for 3D printed porous structures

Scientific Reports
In this work, we provide a novel BCC porous structure to explore the effect of topological configuration on mechanical properties through computer-aided design.
Yuan Li, Xiangyu Ma
doaj   +1 more source

Fabrication of GaOx Confinement Structure for InGaN Light Emitter Applications

Crystals, 2018
An indium gallium nitride (InGaN) light-emitting diode (LED) with an embedded porous GaN reflector and a current confined aperture is presented in this study. Eight pairs of n+-GaN:Si/GaN in stacked structure are transformed into a conductive, porous GaN/
Yi-Yun Chen, Yuan-Chang Jhang, Chia-Jung Wu, Hsiang Chen, Yung-Sen Lin, Chia-Feng Lin   +5 more
doaj   +1 more source