Results 131 to 140 of about 814,962 (250)

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

Advanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang, Wenzhuo Yang, Wenting Cheng, Jing Zuo, Lin Pan, Sheng Zhong, Ren Geng, Yao Zhao, Zijian Chen, Canhua Huang, Yang Bai, Liyan Zhao, Yunqian Li   +12 more
wiley   +1 more source

Wafer‐Scale Dendritic Nanoporous Platinum Films for Neural Electrodes

Advanced Science, EarlyView.
Wafer‐scale dendritic nanoporous platinum films with intrinsic nanoscale porosity are synthesized by suraface‐confined wet chemistry and transferred onto flexible substrates to create tissue‐conformal neural electrodes. The ultrathin films combine mechanical flexibility with electrochemical stability, enabling low‐impedance, high‐capacitance interfaces
Kyeongbin Kang, Joosung Oh, Soumen Dutta, Sun Woo Jang, Byeong Su Gu, Woosung Cho, Mingyu Kwak, Sunguk Hong, Seongjae Lee, Hyo Kyoung Jeon, Juwan Han, Keehoon Kim, Sung‐Min Park, Unyong Jeong, In Su Lee   +14 more
wiley   +1 more source

Hydroxyapatite/Titania sol-gel coatings on porous titanium-niobium shape memory alloy for bone implants

, 2008
Hydroxyapatite/Titania sol-gel coatings on porous titanium-niobium shape memory alloy for bone ...
C Wen (13447692), Peter Hodgson (13089276), Y Li (4701352), Jianyu Xiong (13076004), J Lin (6951434)   +4 more
core  

Highly Porous Titanium Acetabular Components in Primary and Revision Total Hip Arthroplasty: A Systematic Review

, 2020
Background: A number of papers have been published reporting on the clinical performance of highly porous coated titanium acetabular cups in primary and revision total hip arthroplasty (THA).
Nikolaou, V.S., Atrey, A., Malahias, M.-A., Greenberg, A., Sculco, P.K., Kostretzis, L.   +5 more
core  

Sustainable Hydrogel‐Forming Microneedle‐Reservoir Patches for Transdermal Delivery of Hydrophilic Macromolecules: Biopolymers, Green Manufacturing and Translation

Advanced Science, EarlyView.
Hydrogel‐forming microneedle (HFMN)‐reservoir patches provide a modular route for controlled transdermal delivery of hydrophilic biomacromolecules. The platform integrates skin‐barrier penetration, sustainable biopolymers, scalable green manufacturing, hydration‐driven transport, model‐cargo validation, and translational quality requirements.
Siddharth Mohanty, Mehmet Onur Aydogdu, Sijia Kang, Xinbo Li, Mohan Edirisinghe   +4 more
wiley   +1 more source

Porous titanium-coated polyetheretherketone implants exhibit an improved bone–implant interface: an in vitro and in vivo biochemical, biomechanical, and histological study

, 2018
Boyle C Cheng,1 Sravanthi Koduri,1 Charles A Wing,2 Natalie Woolery,3 Daniel J Cook,1 Robert C Spiro2,3 1Neuroscience Institute, Allegheny Health Network, Pittsburgh, PA 15212, USA; 2Research and Development, Aesculap Implant Systems, LLC, Breinigsville,
Cheng BC, Cook DJ, Koduri S, Spiro RC, Wing CA, Woolery N   +5 more
core  

Controlling Epitaxial Zn Growth via Guided Laser Patterning toward High‐Performance 6Ah Aqueous Zn||I2 Batteries

Advanced Science, EarlyView.
A scalable laser‐assisted surface patterning method regulates zinc ion flux and promotes lateral epitaxial growth for stable aqueous batteries. Periodic micro‐holes effectively minimize interfacial resistance and reconstruct the zinc texture to favor the compact (002) basal plane. This structured anode suppresses both dendrite propagation and parasitic
Suyeon Kim, Dongjae Kim, Youngeun Kim, Chaejeong Kim, Myunghyun Ryu, Wooyoung Jin, Hyeokjin Kwon, Kyu‐Nam Jung, Ki Jae Kim, Jong‐Won Lee, Jinhong Lee   +10 more
wiley   +1 more source

Mn/Zn Bimetallic MOF‐Integrated Hydrogel Alleviates Excessive Mitochondrial Fission in BMSCs to Promote Osteoporotic Jawbone Repair

Advanced Science, EarlyView.
Excessive reactive oxygen species (ROS) and chronic inflammation impair bone marrow‐derived mesenchymal stem cells (BMSCs), contributing to poor healing in osteoporotic jawbone defect. The gelatin methacryloyl hydrogel loaded with manganese‐doped zeolitic imidazolate framework (Mn‐ZIF‐8@GelMA) promotes regeneration through redox regulation and ...
Xiayue Jin, Shengjia Ye, Yun Yuan, Xueying Yang, Jiarui Cui, Hongming Zhang, Hui Huang   +6 more
wiley   +1 more source

PIAS3 CircRNA‐Loaded Lipid Nanoparticles Restore ALOX15 SUMOylation to Suppress Cementoblast Ferroptosis and Attenuate Orthodontically Induced Root Resorption

Advanced Science, EarlyView.
Orthodontic compression suppresses PIAS3 expression in cementoblasts, impairing ALOX15 SUMOylation and ubiquitin‐mediated degradation, which leads to ALOX15 accumulation, lipid peroxidation, ferroptosis, and osteoclastogenesis. Local delivery of PIAS3 circRNA‐loaded lipid nanoparticles restores the PIAS3–ALOX15 regulatory pathway, alleviates ...
Yifei Hou, Chongzheng Yan, Xinrui Xu, Zihan Yang, Xinhui Wu, Hongxu Zhao, Xuan Song, Jianing Zhang, Yijing Li, Aohua Yang, Xiamei Lu, Yi Liu   +11 more
wiley   +1 more source

Efficient Powder Removal and Micro-Nano Structural Formation in 3D-Printed Porous Titanium Implants for Enhanced Osteogenesis. [PDF]

Biomater Res
Tang J, Li S, Liu Y, Liu C, Pei G, Wang L, Yan M, Zhao D.   +7 more
europepmc   +1 more source