Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma +8 more
wiley +1 more source
Mechanical and biological properties of 3D-printed porous titanium scaffolds coated with composite growth factors. [PDF]
Jiang C +10 more
europepmc +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source
The cervical interbody cage needs to take both biomechanical and biological requirements into account. Here, a new‐style degradable, multicomponent, and bioinspired nacre‐like cervical interbody cage composite, which exhibits promising mechanical‐support‐related behavior and osteogenesis‐related potential, is designed and prepared.
Xiu‐Wu Guo +8 more
wiley +1 more source
Correction: 3D-printed porous titanium rods equipped with vancomycin-loaded hydrogels and polycaprolactone membranes for intelligent antibacterial drug release. [PDF]
Ma Z +7 more
europepmc +1 more source
Integrating chemo‐mechanical cues in nano‐microscale environments for stem cell regulation
Nano/microscale control strategies, including nano/microscale materials, ligand spacings, and cell encapsulating gels, cell mechanics, integrin signaling, and biochemical cues to direct stem cell fate, tissue regeneration, and organoid engineering, enabling advanced biomedical applications through mechanoregulation at cell‐material interfaces ...
Rajendra K. Singh +5 more
wiley +1 more source
Low-Intensity Pulsed Ultrasound Promotes Osteogenesis in Porous Titanium Alloys Through miR-1187/BMP4 Pathway. [PDF]
Qin L, Cao H, Liu X, Zhang D, Wu L.
europepmc +1 more source
A defined 700 nm low‐density nanotopographical interface mechanically primes MSCs through the integrin β1–focal adhesion–Akt–Rab27a‐dependent pathway, enhancing exosome secretion and osteoinductive potency. Enrichment of miR‐548d‐5p in these exosomes promotes osteogenic differentiation and bone regeneration, establishing nanotopography‐guided MSC ...
Ziqi Zhang +12 more
wiley +1 more source
The use of porous titanium acetabular augments in primary total hip arthroplasty for hip dysplasia or rapidly destructive coxopathy. [PDF]
Sugano N +6 more
europepmc +1 more source
Graphene Materials for Sustainable Energy Applications: A Contemporary Perspective
ABSTRACT Graphene has garnered significant attention as a promising material with great potential for contributing to sustainable energy initiatives, such as RE100 (100% renewable energy initiative) and CF100 (100% carbon‐free initiative). This review aims to explore the potential of graphene for advancing renewable energy applications by highlighting
Niraj Kumar +3 more
wiley +1 more source

