Results 11 to 20 of about 495 (140)

Molecular Design Learned from the Natural Product Porphyra-334: Molecular Generation via Chemical Variational Autoencoder versus Database Mining via Similarity Search, A Comparative Study. [PDF]

ACS Omega, 2022
A comparative study is presented. The method via chemical variational autoencoder (VAE) and the method via similarity search are compared, focusing on their generation ability for new functional molecular design. Focusing on the natural porphyra-334 as a model molecule, we generated three groups: molecules of mycosporine-like amino acids (MAAs) as ...
Harada Y, Hatakeyama M, Maeda S, Gao Q, Koizumi K, Sakamoto Y, Ono Y, Nakamura S.   +7 more
europepmc   +4 more sources

"Button-on-a-String" Mechanism in Water, the Ultrafast UV-to-Heat Conversion by Mycosporine-like Amino Acid Porphyra-334 of Natural Sunscreen Compound. [PDF]

ACS Phys Chem Au
Mycosporine-like amino acids (MAAs) are a family of hydrophilic sunscreen compounds synthesized by aquatic organisms, such as algae and cyanobacteria. In this study, we demonstrate that porphyra-334, which is a common MAA, decays nonradiatively within several hundred femtoseconds after ultraviolet (UV) light absorption in water by rotating the ...
Hatakeyama M, Nakamura S.
europepmc   +4 more sources

Porphyra-334, a mycosporine-like amino acid, attenuates UV-induced apoptosis in HaCaT cells [PDF]

Acta Pharmaceutica, 2017
The main aim of the current research was to study the effect of porphyra-334, one of mycosporine-like amino acids (MAAs), well known as UV-absorbing compounds, on UVinduced apoptosis in human immortalized keratinocyte (HaCaT) cells.
Suh Sung-Suk, Oh Se Kyung, Lee Sung Gu, Kim Il-Chan, Kim Sanghee   +4 more
doaj   +3 more sources

Distinct characteristics of DNA field effect transistors embedded with marine-derived porphyra-334 under UV illumination [PDF]

AIP Advances, 2019
DNA extracted from salmon has recently attracted the attention of researchers, resulting in applications of DNA in photonic and electronic devices.
Prathamesh Chopade, Sang Hyun Moh, Vinit Kanade, Taesung Kim, Atul Kulkarni, Sung Ha Park   +5 more
doaj   +2 more sources

Phytochemical Diversity, Nutritional Values, and Biological Properties of <i>Halopithys incurva</i> (Hudson) Batters, 1902. [PDF]

Food Sci Nutr
Halopithys incurva is a red macroalga distributed across the Mediterranean Sea and North‐East Atlantic, with occasional reports from the Indian Ocean. It exhibits a rich chemical diversity, including isoflavones, bromophenols, MAAs, pigments, phycobiliproteins, primary metabolites, and neuroactive compounds.
Aalilou Y, Bouyahya A, Benrahou K, Hassoun M, Moussa H, El Hassani IA, Al Abdulmonem W, Lee LH, Zengin G, Faouzi MEA.   +9 more
europepmc   +2 more sources

Nitrogen Substrate Impacts Microcystis aeruginosa Exometabolome Composition. [PDF]

Environ Microbiol Rep
We used untargeted metabolomics to identify differences in the compounds exuded into culture media by three strains of M. aeruginosa grown on three N substrate treatments (NO3−, NH4+, and urea). Results showed that the usage of different N substrates changes the exometabolome of toxic and non‐toxic strains of M. aeruginosa.
Peck CM, Hart LN, Kersten R, Kharbush JJ.   +3 more
europepmc   +2 more sources

Synthesis of Amines for Active Pharmaceutical Ingredients Using the Whole-Cell Factory Saccharomyces Cerevisae. [PDF]

Chembiochem
This review highlights advances in engineering Saccharomyces cerevisiae for the sustainable biocatalytic production of pharmaceutically relevant amines, amino alcohols, amino acids, and complex alkaloids. It focuses on strategies to increase productivity, including enhanced enzyme expression, cofactor regeneration, precursor channeling, pathway ...
Kwiatos N, Ossel S, Mutti FG.
europepmc   +2 more sources

Transcriptome Profiling of Human Follicle Dermal Papilla Cells in response to Porphyra-334 Treatment by RNA-Seq. [PDF]

Evid Based Complement Alternat Med, 2021
Porphyra-334 is a kind of mycosporine-like amino acid absorbing ultraviolet-A. Here, we characterized porphyra-334 as a potential antiaging agent. An in vitro assay revealed that porphyra-334 dramatically promoted collagen synthesis in fibroblast cells. The effect of porphyra-334 on cell proliferation was dependent on the cell type, and the increase of
Kim SY, Cho WK, Kim HI, Paek SH, Jang SJ, Jo Y, Choi H, Lee JH, Moh SH.   +8 more
europepmc   +4 more sources

Physiology and chemistry integration under UV-B across green algal <i>Klebsormidium</i> clades (Streptophyta) reveals constitutive and inducible MAA-associated photoprotective responses. [PDF]

Front Microbiol
Stratospheric ozone variability continues to modulate biologically harmful UV-B radiation, exerting strong selective pressure on terrestrial green algae.
Ballık B, Hammerle F, Pita FM, Görünmek M, Omidi A, Grappadelli AC, Liang W, Oberosler A, Karsavran K, Çamur GN, Plag N, Çakmak ZE, Herburger K, Ganzera M, Çakmak T, Karsten U.   +15 more
europepmc   +2 more sources

Shinorine and porphyra-334 isolated from laver (Porphyra dentata) inhibit adipogenesis in 3T3-L1 cells. [PDF]

Food Sci Biotechnol, 2022
Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from Porphyra spp. are bioactive compounds with strong photoprotective and antioxidant properties. In this study, the anti-adipogenic effect of shinorine and porphyra-334 was examined in vitro utilizing 3T3-L1 preadipocytes.
Choi SY, Lee SY, Kim HG, Jeong JC, Batara DC, Kim SH, Cho JY.   +6 more
europepmc   +3 more sources