Efficient production of mycosporine-like amino acids, natural sunscreens, in Yarrowia lipolytica [PDF]
Biotechnology for Biofuels and Bioproducts, 2023 Background Mycosporine-like amino acids (MAAs), including shinorine and porphyra-334, are gaining attention as safe natural sunscreens. The production of MAAs has been achieved in diverse microbial hosts, including Saccharomyces cerevisiae.
Hyunbin Jin +4 more
doaj +2 more sources
Occurrence of Mycosporine-like Amino Acids (MAAs) from the Bloom-Forming Cyanobacteria Aphanizomenon Strains [PDF]
Molecules, 2022 Mycosporine-like amino acids (MAAs) are widespread in various microbes and protect them against harsh environments. Here, four different Aphanizomenon species were isolated from severely eutrophic waterbodies, Lake Dianchi and the Guanqiao fishpond ...
Hang Zhang +7 more
doaj +2 more sources
Temperature-driven metabolic acceleration independent of cell growth enables high-level production of d-ribulose and shinorine in Streptomyces lividans [PDF]
Biotechnology for Biofuels and BioproductsBackground Temperature strongly influences cellular metabolism through its effects on enzyme activity. Although the optimal growth temperature generally reflects the collective temperature dependence of enzymes involved in proliferation, the optimal ...
Jun Sakurai +7 more
doaj +2 more sources
Reversing the directionality of reactions between non-oxidative pentose phosphate pathway and glycolytic pathway boosts mycosporine-like amino acid production in Saccharomyces cerevisiae [PDF]
Microbial Cell FactoriesBackground Mycosporine-like amino acids (MAAs) are a class of strongly UV-absorbing compounds produced by cyanobacteria, algae and corals and are promising candidates for natural sunscreen components.
Miselle Tiana Hengardi +6 more
doaj +2 more sources
Efficient Isolation of Mycosporine-Like Amino Acids from Marine Red Algae by Fast Centrifugal Partition Chromatography [PDF]
Marine Drugs, 2022 Marine rhodophyta are known to synthesize specific secondary metabolites, mycosporine-like amino acids (MAAs), to protect themselves from harmful UV-radiation. Shinorine and porphyra-334 are among the most abundant representatives of this compound class.
Michael Zwerger +2 more
doaj +2 more sources
Separating and Purifying Mycosporine-like Amino Acids from Cyanobacteria for Application in Commercial Sunscreen Formulations [PDF]
BioTech, 2023 Using algal-derived mycosporine-like amino acids (MAAs) in sunscreen formulations is constrained by low cellular concentrations of MAAs and by the high costs associated with harvesting algal cells and extracting the MAAs.
Valeria Candelo, Carole Anne Llewellyn
doaj +2 more sources
Development of CRISPR-Cas9-based genome editing tools for non-model microorganism Erwinia persicina [PDF]
Synthetic and Systems BiotechnologyErwinia persicina is a bacterium that has been known to produce secondary metabolites, such as andrimid, pink pigment, and exopolysaccharides, and to infect more than twenty plant species. However, traditional gene manipulation methods have been hindered
Tingfeng Cheng +3 more
doaj +2 more sources
Immunomodulatory Effects of the Mycosporine-Like Amino Acids Shinorine and Porphyra-334
Marine Drugs, 2016 Mycosporine-like amino acids (MAAs) are secondary metabolites, produced by a large variety of microorganisms including algae, cyanobacteria, lichen and fungi. MAAs act as UV-absorbers and photo-protectants.
Markus Ganzera +2 more
exaly +3 more sources
Isolation of Mycosporine-like Amino Acids from Red Macroalgae and a Marine Lichen by High-Performance Countercurrent Chromatography: A Strategy to Obtain Biological UV-Filters [PDF]
Marine Drugs, 2023 Marine organisms have gained considerable biotechnological interest in recent years due to their wide variety of bioactive compounds with potential applications.
Julia Vega +6 more
doaj +2 more sources
Photomorphogenic and Biochemical Effects of Radiation and Nitrate Availability on the Red Alga Plocamium cartilagineum [PDF]
PlantsNon-photosynthetic photoreceptors detecting different wavelength ranges in the UV and visible region of spectra may trigger algal acclimation and homeostasis. We studied Plocamium cartilagineum responses based on the saturation of photosynthesis by Amber
Bruna Rodrigues Moreira +6 more
doaj +2 more sources