Results 11 to 20 of about 453 (130)

Physiology and chemistry integration under UV-B across green algal Klebsormidium clades (Streptophyta) reveals constitutive and inducible MAA-associated photoprotective responses [PDF]

Frontiers in Microbiology
Stratospheric ozone variability continues to modulate biologically harmful UV-B radiation, exerting strong selective pressure on terrestrial green algae.
Barış Ballık, Barış Ballık, Fabian Hammerle, Fernanda Miyagi Pita, Fernanda Miyagi Pita, Mihraç Görünmek, Mihraç Görünmek, Azam Omidi, Allegra Corelli Grappadelli, Wenxin Liang, Armin Oberosler, Kader Karsavran, Kader Karsavran, Gamze Nur Çamur, Gamze Nur Çamur, Niklas Plag, Niklas Plag, Zeynep Elibol Çakmak, Zeynep Elibol Çakmak, Klaus Herburger, Markus Ganzera, Turgay Çakmak, Turgay Çakmak, Ulf Karsten   +23 more
doaj   +2 more sources

Genomic and secondary metabolites of the marine cyanobacterium Capilliphycus salinus ALCB114379. [PDF]

J Phycol
Abstract Assembling high‐quality genomes from underexplored environments can be helpful for understanding microbial diversity and identifying novel species. The Cyanobacterium type strain Capilliphycus salinus ALCB114379 is a representative of Oscillatoriales order isolated from a supralittoral zone of the south Atlantic Ocean in Brazil, an ecotone ...
Passos GS, Dextro RB, Machado MJ, Feitosa AMT, Silva NP, Cruz RB, Andreote APD, Pinto E, Fiore MF.   +8 more
europepmc   +2 more sources

Efficient Production of Shinorine and Mycosporine-Glycine-Alanine in <i>Yarrowia lipolytica</i> Using Natural and Engineered Nonribosomal Peptide Synthetases. [PDF]

J Agric Food Chem
Mycosporine-like amino acids (MAAs) are ultraviolet-absorbing metabolites with recognized photoprotective and pharmacological benefits, predominantly found in marine organisms. Due to the inefficiency of extraction from natural sources, microbial biosynthesis using heterologous hosts is an attractive alternative.
Lee D, Jin H, Kim S, Kim S, Park E, Yoo D, Hahn JS.   +6 more
europepmc   +4 more sources

Direct Evidence of Microbial Sunscreen Production by Scum-Forming Cyanobacteria in the Baltic Sea. [PDF]

Environ Microbiol Rep
We found both culture‐independent and culture‐dependent evidence for the widespread production of mycosporine‐like amino acids (MAAs) in blooms of cyanobacteria from the Baltic Sea. Using a combination of bioinformatics, microbial genetics, and mass spectrometry, we demonstrated the high‐level production of these microbial sunscreens in members of the ...
Vuori I, Gaiani G, Arsın S, Delbaje E, Järn J, Snårbacka R, Couëdelo A, Murukesan G, Wahlsten M, Jokela J, Shishido TK, Fewer DP.   +11 more
europepmc   +2 more sources

Nitrogen Substrate Impacts Microcystis aeruginosa Exometabolome Composition. [PDF]

Environ Microbiol Rep
We used untargeted metabolomics to identify differences in the compounds exuded into culture media by three strains of M. aeruginosa grown on three N substrate treatments (NO3−, NH4+, and urea). Results showed that the usage of different N substrates changes the exometabolome of toxic and non‐toxic strains of M. aeruginosa.
Peck CM, Hart LN, Kersten R, Kharbush JJ.   +3 more
europepmc   +2 more sources

Synthesis of Amines for Active Pharmaceutical Ingredients Using the Whole-Cell Factory Saccharomyces Cerevisae. [PDF]

Chembiochem
This review highlights advances in engineering Saccharomyces cerevisiae for the sustainable biocatalytic production of pharmaceutically relevant amines, amino alcohols, amino acids, and complex alkaloids. It focuses on strategies to increase productivity, including enhanced enzyme expression, cofactor regeneration, precursor channeling, pathway ...
Kwiatos N, Ossel S, Mutti FG.
europepmc   +2 more sources

Phytochemical Diversity, Nutritional Values, and Biological Properties of <i>Halopithys incurva</i> (Hudson) Batters, 1902. [PDF]

Food Sci Nutr
Halopithys incurva is a red macroalga distributed across the Mediterranean Sea and North‐East Atlantic, with occasional reports from the Indian Ocean. It exhibits a rich chemical diversity, including isoflavones, bromophenols, MAAs, pigments, phycobiliproteins, primary metabolites, and neuroactive compounds.
Aalilou Y, Bouyahya A, Benrahou K, Hassoun M, Moussa H, El Hassani IA, Al Abdulmonem W, Lee LH, Zengin G, Faouzi MEA.   +9 more
europepmc   +2 more sources

Natural Product Gene Clusters in the Filamentous Nostocales Cyanobacterium HT-58-2

Life, 2021
Cyanobacteria are known as rich repositories of natural products. One cyanobacterial-microbial consortium (isolate HT-58-2) is known to produce two fundamentally new classes of natural products: the tetrapyrrole pigments tolyporphins A–R, and the ...
Xiaohe Jin, Eric S. Miller, Jonathan S. Lindsey   +2 more
doaj   +1 more source

Metabolic engineering of Corynebacterium glutamicum for production of sunscreen shinorine [PDF]

Bioscience, Biotechnology, and Biochemistry, 2018
Abstract Ultraviolet-absorbing chemicals are useful in cosmetics and skin care to prevent UV-induced skin damage. We demonstrate here that heterologous production of shinorine, which shows broad absorption maxima in the UV-A and UV-B region.
Yota, Tsuge, Hideo, Kawaguchi, Shogo, Yamamoto, Yoshiko, Nishigami, Masahiro, Sota, Chiaki, Ogino, Akihiko, Kondo   +6 more
openaire   +2 more sources

Shinorine and porphyra-334 isolated from laver (Porphyra dentata) inhibit adipogenesis in 3T3-L1 cells. [PDF]

Food Sci Biotechnol, 2022
Mycosporine-like amino acids (MAAs) such as shinorine and porphyra-334 from Porphyra spp. are bioactive compounds with strong photoprotective and antioxidant properties. In this study, the anti-adipogenic effect of shinorine and porphyra-334 was examined in vitro utilizing 3T3-L1 preadipocytes.
Choi SY, Lee SY, Kim HG, Jeong JC, Batara DC, Kim SH, Cho JY.   +6 more
europepmc   +3 more sources