Results 171 to 180 of about 167,383 (325)

A pH‐Sensitive Nanosized Covalent–Organic Polymer for Enhanced Tumor Photodynamic Immunotherapy by Hypoxia Relief and STAT3 Inhibition

open access: yesAdvanced Science, EarlyView.
The nanosized covalent organic polymer composed of photosensitizer porphyrin, pyruvate kinase inhibitor vitamin K3, and STAT3 inhibitor WP1066 is prepared for enhanced photodynamic immunotherapy by simultaneous hypoxia relief and STAT3 inhibition. Abstract Photodynamic therapy (PDT) is a promising cancer therapy modality by generating reactive oxygen ...
Lei Lei   +7 more
wiley   +1 more source

Exploration of Oxygen Reduction Reaction Catalyzed by FePPc and Pz‐FeTPr Conjugated Organic Polymer: Insights From Grand‐Canonical Density Functional Theory

open access: yesAdvanced Science, EarlyView.
At alkaline conditions (pH = 13), for FePPc and Pz‐FeTPr at low potential (less than 0.5 V), the ORR mechanism is the *O2 mechanism (O2→∗O2→∗OOH→∗O→∗OH→H2O${{\rm{O}}_2} \to ^*{O_2} \to ^*OOH \to ^*O \to ^*OH \to {H_2}O$), Fe is the active site; for Pz‐FeTPr at high potential (larger than 0.5 V), the Fe site is covered by O2−$O_2^ - $, the nearby C site
Pengfei Yuan   +5 more
wiley   +1 more source

Fullerene C70‐Encapsulated Tetrathiafulvalene‐Co Porphyrin Covalent Organic Framework: Driving Multistep Charge Transfer to Boost CO2 Photoreduction

open access: yesAdvanced Science, EarlyView.
The encapsulation of C70 into COF has improved the efficiency of photocatalytic CO2 reduction significantly. The introduction of C70 drives multistep charge transfer and forms a long‐lived charge‐separated state. It also thermodynamically lowers the energy barrier of the rate‐determining step.
Ying Jiang   +8 more
wiley   +1 more source

Biomimetic Analysis of Neurotransmitters for Disease Diagnosis through Light‐Driven Nanozyme Sensor Array and Machine Learning

open access: yesAdvanced Science, EarlyView.
A novel photoresponsive nanozyme sensor array, combining metal‐organic frameworks (MOFs) with advanced machine learning algorithms, provides a breakthrough in rapid neurotransmitter detection and disease diagnostics. This sensor array is capable of accurately identifying neurotransmitter profiles associated with neurological disorders, offering ...
Kun Yu   +9 more
wiley   +1 more source

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