Results 161 to 170 of about 35,071 (303)

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Porphyromonas gingivalis y enfermedades sistémicas

, 2015
Porphyromonas gingivalis (P.g.) is a gram-negative coccobacillus that resides in the gingival sulcus. Some of its structural pathogenic factors like fimbriae allow its adhesion to the tissues of the gingival sulcus, where P.g.
Fandiño Henao, Vanessa, Orrego Cardozo, Mary, Salgado Morales, Yenny Paola, Parra Gil, María Alejandra, Muñoz Guarín, Erika   +4 more
core  

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Colonization by Porphyromonas gingivalis in cervical squamous cell carcinomas promotes metastasis through FimA/CD151/ITGB1 signaling

Journal of Translational Medicine
Background Cervicovaginal microbiota dysbiosis has been implicated in the progression of cervical cancer. Recent studies have reported an increased abundance of Porphyromonas species in the vaginal microbiota of cervical cancer patients.
Xiuting Huang, Yuan Zhuang, Rui Wang, Jing Qu, Yuanyang Tan, Liang Li, Wenjun Pan, Huilong Nie, Kefeng Li, Yujing Lin, Liutong Yi, Xiaoyu Feng, Huimin Lan, Guangxue Wang, Xiantao Zeng, Zhenqi Jiang, De-Yun Wang, Yongkang Qiao, Yan Yan   +18 more
doaj   +1 more source

Association Between Porphyromonas gingivalis and Alzheimer’s Disease: A Comprehensive Review

Jéssica María Sarmiento-Ordóñez,1,2 Dayvid Rafael Brito-Samaniego,3 Ana Cristina Vásquez-Palacios,1 Edisson-Mauricio Pacheco-Quito1,2 1Unidad Académica de Salud y Bienestar, Facultad de Odontología, Universidad Católica de Cuenca, Cuenca, Ecuador; 2Grupo
Pacheco-Quito EM, Brito-Samaniego DR, Vásquez-Palacios AC, Sarmiento-Ordóñez JM   +3 more
core  

Hydrogels in Periodontal and Craniofacial Regeneration: Current Applications and Next‐Generation Biomaterials

Journal of Periodontal Research, EarlyView.
Hydrogel‐based therapies have proven to be valuable tools to address the unique regeneration challenges of complex multi‐domain periodontal and craniofacial tissues. This review highlights and classifies clinically approved and emerging hydrogel therapies indicated for the regeneration of periodontal and craniofacial tissues.
Z. Gouveia, M. Diba, B. T. Yilmaz, Jae‐Kook Cha, D. T. Wu, D. J. Mooney   +5 more
wiley   +1 more source

Multi-omics investigation of Porphyromonas gingivalis exacerbating acute kidney injury through the gut-kidney axis

mSystems
Periodontitis is closely related to renal health, but the specific influence of Porphyromonas gingivalis (P. gingivalis), a key pathogen in periodontitis, on the development of acute kidney injury (AKI) in mice has not been fully elucidated. In our study,
Ling Dong, Zhaoxin Ji, Jing Sun, Jiangqi Hu, Qingsong Jiang, Wei Wei   +5 more
doaj   +1 more source

Effect of Porphyromonas gingivalis on pre-osteoblastic cells MC3T3-E1

Antecedentes: La periodontitis es una enfermedad inflamatoria crónica, multifactorial, que afecta los tejidos de soporte dental, además es el resultado de la interacción de factores ambientales, bacterianos y del hospedador.
Muriel Rios, Mariana
core   +1 more source

A Multifunctional β‐Defensin‐3 Mimetic Peptide Modulates Host–Biofilm Interactions and Reduces Bone Loss in Periodontitis

Journal of Periodontal Research, EarlyView.
BDMP, a peptide that can penetrate cells and tissues, offering antimicrobial and anti‐inflammatory effects, has been identified as a potential new therapy for periodontitis. ABSTRACT Aim This study evaluated the potential of a beta‐defensin‐3 mimetic peptide (BDMP), a synthetic cell‐penetrating peptide with antimicrobial and immunomodulatory properties,
Beom Soo Jo, Dong Woo Lee, Ji‐Young Lee, Sanghui Seok, Yu‐Bin Kim, Jue‐Yeon Lee, Shin‐Young Park, Young Dan Cho, Yang Jo Seol, Yoon Shin Park, Shahram Ghanaati, Homayoun H. Zadeh, Chong Pyung Chung, Yoon Jeong Park   +13 more
wiley   +1 more source

A Pulmonary Abscess Caused by Porphyromonas gingivalis Infection: A Case Report and Literature Review

The Clinical Respiratory Journal
Lung abscess is a common disease in respiratory medicine, which is a suppurative lesion caused by various pathogens, and microbiological examination is crucial for the treatment of lung abscess.
Xu Chen, Ling Wu, Ruoxi Wu, Jiajia Dong
doaj   +1 more source