Results 141 to 150 of about 24,941 (264)

Efficacy of a Hyaluronic Acid‐Based Gel Versus 0.20% Chlorhexidine in Nonsurgical Periodontal Therapy: A Single‐Blind Randomized Clinical Trial

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective To compare the adjunctive efficacy of a hyaluronic acid (HA) gel with 0.20% chlorhexidine (CHX) during nonsurgical periodontal therapy in periodontal patients over 6 months. Methods A single‐blind, randomized, controlled trial included 40 healthy, nonsmoking adults with periodontitis.
Andrea Scribante   +4 more
wiley   +1 more source

Oxidative Stress–Driven Alterations in FoxO‐1 and MMP‐9 Activity in Smoking‐Associated Periodontitis

open access: yesOral Diseases, EarlyView.
ABSTRACT Objectives Smoking disrupts oxidative balance and is a major risk factor for periodontitis. Forkhead box protein O‐1 (FoxO‐1) regulates antioxidant defense, yet its contribution to smoking‐associated periodontal breakdown is unclear. This cross‐sectional case–control study assessed reactive oxygen species (ROS), matrix metalloproteinase‐9 (MMP‐
Fatma Oner   +4 more
wiley   +1 more source

Influence of Vitamin D Concentration and Glycaemic Control on the Severity of Periodontitis in Cameroonian Type 2 Diabetics: A Cross‐Sectional Study

open access: yesOral Diseases, EarlyView.
ABSTRACT Background This cross‐sectional study aimed to evaluate the influence of vitamin D and glycaemic control on the severity of periodontitis in Cameroonian type 2 diabetics (T2D) and to identify the determinants of severe periodontitis (SP). Methods Vitamin D concentration and blood glucose control were determined by measuring serum levels of 25 ...
Lawrence Essama Eno Belinga   +8 more
wiley   +1 more source

Red‐Complex Bacterial DNA in Carotid Atheroma of Dentate and Long‐Term Edentulous Patients and Its Association With Mitochondrial DNA Copy Number

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective This study aimed to evaluate (i) the presence of red complex bacteria in carotid atheroma plaques of dentate and edentulous patients and (ii) the possible relationship between mitochondrial DNA copy number (mtDNA‐cn), an indicator of mitochondrial function, and periodontal disease.
Ayşe Toraman   +4 more
wiley   +1 more source

Periodontitis‐Associated Bacteria and Their Connection to Proinflammatory Biomarkers in Periodontal Pockets: A Clinical Microbiological Study

open access: yesOral Diseases, EarlyView.
ABSTRACT Background This study examines the relationship between the microbial load of selected periodontitis‐associated bacteria (PAB) and proinflammatory biomarkers in gingival crevicular fluid (GCF) from patients with periodontitis. Methods GCF and subgingival biofilm samples were collected from the deepest periodontal pocket of each quadrant of 515
Nils Werner   +9 more
wiley   +1 more source

Association Between Periodontitis and Respiratory Diseases: A Systematic Umbrella Meta‐Analysis

open access: yesOral Diseases, EarlyView.
ABSTRACT Aim This study aimed to evaluate the association between periodontitis and respiratory diseases using an umbrella meta‐analysis. Methods Meta‐analyses (MAs) reporting odds ratios (OR) and mean differences (MD) for the association between periodontitis and respiratory diseases of COVID‐19, chronic obstructive pulmonary disease (COPD), asthma ...
Shahen Hiwa Omer   +4 more
wiley   +1 more source

Heterogeneous Systemic IgG Responses to Porphyromonas gingivalis Gingipains in Advanced Periodontitis. [PDF]

open access: yesClin Exp Dent Res
Büttner S   +6 more
europepmc   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

open access: yesMolecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai   +7 more
wiley   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

open access: yesMolecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin   +6 more
wiley   +1 more source

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