Results 121 to 130 of about 35,071 (303)
Background P-113 (AKRHHGYKRKFH-NH2) is a 12-amino-acid histidine-rich peptide derived from histatin 5 that is highly degradable in high salt concentrations and biological fluids such as serum, plasma and saliva.
Hong-yan Wang +7 more
doaj +1 more source
Abstract The APOE4 gene, particularly the ε4 allele, is linked to susceptibility to Alzheimer's disease, and periodontitis can cause pathological changes in multiple organs, but combined effects of these conditions and the impact of tumor necrosis factor (TNF)‐α regulation on the combined effects remain unclear.
Ae Ri Kim +2 more
wiley +1 more source
Genotypic and phenotypic characterization of Porphyromonas gingivalis in relation to virulence
The present thesis was designed to increase the knowledge on the role of pathogenic potential of Porphyromonas gingivalis as a putative periodontal pathogen. P. gingivalis was selected to be the model species for periodontal pathogens based on expressing
Yoshino, Takashi
core
Background: Porphyromonas gingivalis is one of the important pathogens in the initiation and progression of periodontitis. The findings regarding the bacterium and periodontal status in geriatric subjects are not widely reported.
Mohamad Aidid, Edre +6 more
core +1 more source
Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin +2 more
wiley +1 more source
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis +5 more
wiley +1 more source
Differences in Immune Response to Porphyromonas gingivalis
ABSTRACT About 341 (average age of 38.0 ± 2.5 years) patients with periodontal disease were included in this study. All the patients were not treated for periodontal disease for a period of 6 months prior to this study. All the patients were not on any hormonal therapy. Antibodies to Porphyromonas gingivalis (P.
Laura M, Tebloeva +4 more
openaire +2 more sources
PhDThere is good evidence that interleukin-I alpha (IL-Ia) plays a key role in both the host response to bacteria and the tissue destruction associated with periodontal disease.
Bostanci, Nagihan
core
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur +6 more
wiley +1 more source
Periodontal diseases and adverse pregnancy outcomes. Present and future
Abstract For more than two decades the possible association between periodontal diseases and adverse pregnancy outcomes has been extensively evaluated. Numerous observational, intervention, and mechanistic studies have offered valuable information on this topic.
Yiorgos A. Bobetsis +3 more
wiley +1 more source

