Porphyromonas gingivalis disrupts hippocampal circadian clock via PI3K/AKT pathway, exacerbating Alzheimer-like pathology. [PDF]
Huang C +6 more
europepmc +1 more source
Novel and emerging antimicrobial strategies in the management of oral infections
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley +1 more source
Antioxidant, Antibacterial, and Antivirulence Activities of a Bioactive Fraction from <i>Lycopus lucidus</i> Against <i>Porphyromonas gingivalis</i>. [PDF]
Park JM +4 more
europepmc +1 more source
Factors affecting the efficacy of nonsurgical therapy of peri‐implantitis
Abstract Objectives and Materials and Methods This article critically reviews the current knowledge on the factors influencing the efficacy of non‐surgical therapy (NST) of peri‐implantitis, taking also advantage of the know‐how from periodontitis management.
Elena Calciolari +4 more
wiley +1 more source
Porphyromonas gingivalis lipids enhance RANKL-mediated osteoclast formation. [PDF]
Zambrello MA +10 more
europepmc +1 more source
Impact of systemic diseases on periodontal remodeling: Mechanisms, mediators, and clinical relevance
Abstract Background Periodontal remodeling is a continuous, adaptive process essential for maintaining the structural and functional integrity of periodontal tissues. While external factors such as bacterial biofilm, excessive forces, and poor oral hygiene are recognized triggers of periodontal pathologies, they do not fully explain their persistent ...
Michael Wolf +7 more
wiley +1 more source
The prognostic value and molecular mechanisms of <i>Porphyromonas gingivalis</i> infection-associated differentially expressed genes in oral squamous cell carcinoma. [PDF]
Song Q +6 more
europepmc +1 more source
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng +4 more
wiley +1 more source
Influence of Implant Positioning on Peri-Implant Colonization by Porphyromonas gingivalis and Fusobacterium nucleatum: A Prospective Longitudinal Observational Cohort Study. [PDF]
Pabri R +5 more
europepmc +1 more source
Understanding exosomes in regenerative dentistry
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad +2 more
wiley +1 more source

