Periodontology 2000, EarlyView.Abstract The primary objective is to critically analyze approaches to local therapy for periodontal disease, particularly in light of its well‐established systemic implications. We specifically address common misconceptions and overestimations regarding the potential of local treatments in contrast to their actual clinical effectiveness.
Andrea Mombelli, Alkisti Zekeridou
wiley +1 more source
<i>Porphyromonas gingivalis</i> Bundled Fimbriae Interact with Outer Membrane Vesicles, Commensals and Fibroblasts. [PDF]
Int J Mol SciLambertz J +4 more
europepmc +1 more source
Engineered surface strategies to manage dental implant‐related infections
Periodontology 2000, EarlyView.Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza +7 more
wiley +1 more source
Microbial crosstalk along the oral-gut axis: organ-specific oncogenic adaptations of Porphyromonas gingivalis and Fusobacterium nucleatum. [PDF]
NeoplasiaWu S, Ye X, Wang J, Li M, Fu Y, Wang S.
europepmc +1 more source
Periodontology 2000, EarlyView.Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje +3 more
wiley +1 more source
Hyaluronic acid: A novel approach in regenerative/reconstructive periodontal therapy?
Periodontology 2000, EarlyView.Abstract Background Although hyaluronic acid (HA) has long been used for many medical applications, only in recent years has it gained greater popularity in the field of periodontics because of its biological effects during wound healing. Even today, most clinicians are not aware that more than one type of HA exists and that the extent of its ...
Andrea Pilloni +7 more
wiley +1 more source
Zebrafish study provides evidence for <i>Porphyromonas gingivalis</i> outer membrane vesicles eliciting Alzheimer's disease-like pathologies. [PDF]
Front Cell Infect MicrobiolGuo J +6 more
europepmc +1 more source
Novel and emerging antimicrobial strategies in the management of oral infections
Periodontology 2000, EarlyView.Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley +1 more source
Development and validation of machine learning-based risk prediction models of coronary artery disease using Porphyromonas gingivalis concentration. [PDF]
BMC Oral HealthZheng X +5 more
europepmc +1 more source
Periodontology 2000, EarlyView.Abstract Aim To evaluate the adjunctive effects of systemic antibiotics (SA) on clinical and microbiological outcomes in the treatment of peri‐implant diseases. Materials and Methods A systematic review and meta‐analysis were conducted following PRISMA guidelines and registered on PROSPERO (CRD420251059056).
Gaetano Isola +5 more
wiley +1 more source