<i>Porphyromonas gingivalis</i> Promotes Neuroinflammation by Microglial Ferroptosis via NOX4/PPAR-α/PGC-1α Pathway. [PDF]
Li X +7 more
europepmc +1 more source
Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents
ABSTRACT Objective To answer the PICoS question ‘in systemically healthy children and adolescents (Population), what are the main features of periodontitis, necrotising periodontal diseases (NPD) and other periodontal conditions (periodontal abscesses, endo‐periodontal lesions, traumatic occlusal forces, prosthesis‐ and tooth‐related factors ...
Inbar Eshkol‐Yogev +5 more
wiley +1 more source
<i>Porphyromonas gingivalis</i> Vesicles Control Osteoclast-Macrophage Lineage Fate. [PDF]
Leon E +17 more
europepmc +1 more source
Gingival and Periodontal Diseases and Conditions in Children and Adolescents: Consensus Report
ABSTRACT Background The objectives of this Focused Workshop were to update the epidemiology, aetiology, risk factors, diagnosis and management of gingival and periodontal diseases and conditions in children and adolescents, and to explore the applicability of the 2018 Classification in children and adolescents.
Iain Chapple +30 more
wiley +1 more source
<i>Porphyromonas gingivalis</i> triggers lipid metabolism disorders in atherosclerosis through the PPARγ-LXRα‑ABCA1/ABCG1 signaling pathway. [PDF]
Lin XJ +12 more
europepmc +1 more source
Macrophage Extracellular Traps in Immunity and Cancer
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
<i>Porphyromonas gingivalis</i> outer membrane vesicles prevent the induction of tolerogenic dendritic cells by first trimester trophoblast cells. [PDF]
Lara B +10 more
europepmc +1 more source
Live <i>Porphyromonas gingivalis</i> and <i>Candida albicans</i> Synergistically Induce RANKL in Osteoblast-like PDLFs But Not in Undifferentiated PDLFs. [PDF]
Abe M +5 more
europepmc +1 more source
Abstract Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder driven by intersecting pathological processes. Persistent attrition in AD drug‐development pipelines highlights the limited clinical impact of single‐target therapies and has increased interest in multi‐target approaches acting on shared biological hubs.
Humberto Martínez‐Orozco +4 more
wiley +1 more source

