Results 241 to 250 of about 55,455 (303)

The Outcome of Intracellular Selenomonas sputigena and its Impact on Gingival Keratinocytes

open access: yesMolecular Oral Microbiology, Volume 41, Issue 3, Page 131-144, June 2026.
ABSTRACT Selenomonas sputigena is an understudied oral pathobiont associated with periodontitis and dental caries. We recently demonstrated that S. sputigena binds to gingival epithelial cells (GECs), where afterwards the bacterium causes robust in vitro pro‐inflammatory cytokine production and migration of monocytes and neutrophils.
Colin G. Hawkes   +6 more
wiley   +1 more source

Porphyromonas gingivalis hijacks mitophagy and lysosomal function to persist in endothelial cells. [PDF]

open access: yesFront Cell Infect Microbiol
Zheng C   +11 more
europepmc   +1 more source

Random Mutagenesis in Porphyromonas gingivalis Enables Isolation of Mutants With Enhanced Secreted Protease Activity

open access: yesMolecular Oral Microbiology, Volume 41, Issue 3, Page 158-164, June 2026.
ABSTRACT Porphyromonas gingivalis is a key pathogen in periodontitis, with secreted proteases as major virulence factors. We developed a screening method to generate and identify P. gingivalis mutants with elevated protease activity. Mutations were induced using the mutagens 2,6‐diaminopurine (2,6‐DAP) or ethyl methanesulfonate (EMS), and the ...
Takeru Nakabayashi   +2 more
wiley   +1 more source

Periodontitis in Patients With Severe Obesity: From the Oral and Gut Microbiota Dysregulation to the Visceral Adipose Tissue Inflammatory and Metabolic Disorders

open access: yesThe FASEB Journal, Volume 40, Issue 9, 15 May 2026.
In patients with severe obesity, periodontitis is associated with oral microbiota dysbiosis which influences gut microbiota composition by increasing Proteobacteria proportion. These alterations are linked to systemic immune and metabolic changes, including higher circulating levels of anti‐Porphyromonas gingivalis lgG and deregulated lipid profile ...
Katy Thouvenot   +11 more
wiley   +1 more source

Living Hydrogels: Harnessing Microorganism–Material Synergy for Next‐Generation Therapeutics

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
 . ABSTRACT Microorganism‐based therapies, particularly those utilizing probiotics, have emerged as a powerful biomedical strategy owing to their inherent living functionalities. These living systems can dynamically interact with host environments and self‐regulate their activity, offering superior adaptability, prolonged functionality, and ...
Shuifang Mao   +3 more
wiley   +1 more source

Porphyromonas gingivalis promotes oral squamous cell carcinoma progression via the IL-6/EZH2/Snai2 axis. [PDF]

open access: yesSci Rep
Liu S   +10 more
europepmc   +1 more source

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