Results 211 to 220 of about 2,737,946 (305)

Intelligent Thermo‐Self‐Limited Magnetothermia with Heat‐Triggered TERT Silencing for Precision Synergetic Cancer Therapy

Advanced Science, EarlyView.
Telomerase reverse transcriptase (TERT) mRNA induces DNA self‐assembly in cancer cells, boosting the nanoplatform's magnetothermal properties. This magnetothermia then activates the Hsp70 promoter, initiating siRNA synthesis to silence the TERT gene, enhancing cancer treatment.
Liang Zhang, Mingfu Gong, Tao Sun, Shilin Xiao, Yue Zhao, Xiaofeng Yang, Wansu Zhang, Chunyu Zhou, Xu Liu, Dong Zhang   +9 more
wiley   +1 more source

Microfluidic‐Driven Lipid Nanoparticles for Improved miRNA Delivery via Endo‐Lysosomal Trafficking Optimization

Advanced Science, EarlyView.
This study investigates the impact of various post‐processing methods (filtration, sonication, dialysis, and heating) on lipid nanoparticles produced using microfluidics. The nanoparticles are designed for efficient delivery of miRNA into cells. The work highlights how processing conditions influence nanoparticle stability and quality, providing ...
Alicja Kosik‐Kozioł, Michał Pruchniewski, Daniel Rybak, Piotr Jenczyk, Karolina Zakrzewska, Magdalena Bartolewska, Sławomir Błoński, Paweł Nakielski, Filippo Pierini   +8 more
wiley   +1 more source

Active Thermal Metasurfaces Enable Superscattering of Thermal Signatures Across Arbitrary Shapes and Thermal Conductivities

Advanced Science, EarlyView.
This study proposes a thermal superscatterer capable of manipulating thermal scattering signatures far exceeding the actual scale of objects. Utilizing transformation thermotics and active thermal metasurfaces, the device reproduces the thermal scattering signature of the enlarged thermal scatterer.
Yichao Liu, Yawen Qi, Fei Sun, Jinyuan Shan, Hanchuan Chen, Yuying Hao, Hongming Fei, Binzhao Cao, Xin Liu, Zhuanzhuan Huo   +9 more
wiley   +1 more source

Single-port vs multi-port laparoscopic appendectomy in acute appendicitis: a systematic review. [PDF]

Langenbecks Arch Surg
Lim EQ, Lim AJK, Lakha A, Razzaq Z.
europepmc   +1 more source

An All‐Soft Wearable Electrochemiluminescence Chip for Sweat Metabolite Detection

Advanced Science, EarlyView.
A wearable electrochemiluminescence chip for sweat metabolite monitoring is pioneered, integrating “all‐soft” components: a flexible closed bipolar electrode (c‐BPE) array based on laser‐induced graphene (LIG), a laser‐cut microfluidic layer for sweat collection, and deep eutectic solvents (DES)‐based conductive ionogels for ECL emission.
Wei Nie, Jie Jiang, Xi Wei, Linfeng Zhuo, Danyang Li, Mingyu Jia, Tianhua Zheng, Hua Cui   +7 more
wiley   +1 more source

Clinical applications of the da Vinci Single-Port robotic system for treatment of colorectal cancer: a narrative review. [PDF]

Ann Surg Treat Res
Choi GS, Kim HJ.
europepmc   +1 more source

Traceless Regulation of Genetic Circuitry

Advanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Feasibility and safety of outside the cage subcostal robotic anatomical lung resections: results of a phase I clinical trial. [PDF]

J Thorac Dis
Bulgarelli Maqueda L, Guimarães Rocha Lima P, Abu-Reida F, Alashgar O, Têtu M, Nasir B, Ferraro P, Liberman M.   +7 more
europepmc   +1 more source

Creating Cell‐Based Hybrid Noodles for Sustainable and Nutrient‐Balanced Diets via a Serum‐Free and Animal‐Free 3D Co‐Differentiation System

Advanced Science, EarlyView.
This study develops a 3D co‐culture and co‐differentiation system for porcine muscle stem cells (pMuSCs) and mesenchymal stem cells (pMSCs) on edible starch‐based scaffolds. The system simultaneously generates myotubes and adipocytes without using serum or chemical inducers.
Xin Guan, Luyi Wang, Wanqiang Sun, Yiwei Feng, Dandan Wang, Haohao Tang, Zhenwu Ma, Guocheng Du, Jian Chen, Jingwen Zhou   +9 more
wiley   +1 more source