Results 51 to 60 of about 402,815 (326)

A Validated Model to Predict Severe Weight Loss in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Severe weight loss in amyotrophic lateral sclerosis (ALS) is common, multifactorial, and associated with shortened survival. Using longitudinal weight data from over 6000 patients with ALS across three cohorts, we built an accelerated failure time model to predict the risk of future severe (≥ 10%) weight loss using five single‐timepoint ...
David G. Lester, Kevin Talbot, Martin R. Turner, Alexander G. Thompson, the Pooled Resource Open‐Access ALS Clinical Trials Consortium   +4 more
wiley   +1 more source

Investigating the Efficacy of Subharmonic Aided Pressure Estimation for Portal Vein Pressures and Portal Hypertension Monitoring [PDF]

Ultrasound in Medicine & Biology, 2012
The efficacy of using subharmonic emissions from Sonazoid microbubbles (GE Healthcare, Oslo, Norway) to track portal vein pressures and pressure changes was investigated in 14 canines using either slow- or high-flow models of portal hypertension (PH).
Daniel B. Brown, Carl L. Chalek, Scott Dianis, Feng Lin, Suhyun Park, Jaydev K. Dave, Jaydev K. Dave, Daniel A. Merton, Hsin Kai Wang, Kai Erik Thomenius, Flemming Forsberg, Jian-Hua Zhou, John R. Eisenbrey, Valgerdur G. Halldorsdottir, Valgerdur G. Halldorsdottir, J.B. Liu   +15 more
openaire   +2 more sources

Application of Rat In Situ Single-pass Intestinal Perfusion in the Evaluation of Presystemic Extraction of Indinavir Under Different Perfusion Rates [PDF]

, 2006
Background/PurposeFirst-pass effect has been an important concern for oral pharmaceuticals. An in vivo system was developed for measuring different concentrations of pharmaceuticals in the portal vein and hepatic vein (via the inferior vena cava) for ...
Ho, Yunn-Fang, Lai, Ming-Yen, Yu, Hsiu-Ying, Huang, Da-Kong, Hsueh, Wei-Cherng, Tsai, Tung-Hu, Lin, Chia-Chun   +6 more
core   +2 more sources

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source

Liver transplantation in patients with patent splenorenal shunts [PDF]

, 1987
Patent distal splenorenal shunts (Warren shunt) have been reported to cause decreases in the portal perfusion pressure and the total hepatic blood flow. Such hemodynamic alterations could have adverse effects on the transplanted liver.
Esquivel, CO, Gordon, RD, Iwatsuki, S, Klintmalm, G, Makowka, L, Starzl, TE, Tzakis, A   +6 more
core  

The use of non-selective beta-blockers in patients with cirrhosis: more doubts than certainties [PDF]

, 2017
In conclusion, prospective RCT would be needed on the use of NSBBs in decompensated cirrhotic patients with ascites however these trials are difficult to organize and will need a large sample size.
Di Gregorio, Vincenza, D’Ambrosio, Daria, Lattanzi, Barbara, Merli, Manuela   +3 more
core   +1 more source

A Comprehensive Review of Clinical Studies on Bacterial Cellulose: From the Earliest Uses to Contemporary Innovations

Advanced Healthcare Materials, EarlyView.
Bacterial cellulose has undergone a transformative journey from early applications to its role in advanced regenerative medicine. The review has a pedagogical ambition, offering clear pathways for future research and clinical adoption. Harmonizing regulatory standards and conducting larger, well‐designed clinical trials with standardized endpoints will
Thomas Meslier, Justin Christopher D'Antin, Gemma Julio, Anna Roig   +3 more
wiley   +1 more source

Mechanochemistry for Metal–Organic Frameworks and Covalent–Organic Frameworks (MOFs, COFs): Methods, Materials, and Mechanisms

Advanced Materials, EarlyView.
An overview is provided of the mechanochemistry of metal‐organic frameworks (MOFs) and covalent‐organic frameworks (COFs), highlighting opportunities and strategies for discovery, synthesis and reactivity studies of these materials. Mechanistic studies and comparisons to the mechanochemistry of organic solids are outlined, showcasing how advances in ...
Joseph M. Marrett, Farshid Effaty, Xavier Ottenwaelder, Tomislav Friščić   +3 more
wiley   +1 more source

Portal Hypertension—Noninvasive Multiparametric Ultrasound‐Based Criteria and Measurements

Portal Hypertension & Cirrhosis
Portal hypertension, the most common complication in liver cirrhosis, is characterized by a pathologic increase in portal venous pressure. Portal hypertension is defined as a pressure gradient greater than 5 mmHg between the portal vein and the inferior ...
Kathleen Möller, Riyad Abu El Hija, Xiaolong Qi, Christian Jenssen, Sven Mutze, Burkhard Möller, Benjamin Misselwitz, Christoph F. Dietrich   +7 more
doaj   +1 more source

Liver Stiffness Measurements in Patients with Non‐cirrhotic Portal Hypertension – The Devil is In the Details [PDF]

, 2018
Non‐cirrhotic portal hypertension (NCPH) is often a diagnostic challenge due to signs and symptoms of portal hypertension that overlap with cirrhosis. The etiology of NCPH is broadly classified as prehepatic, hepatic (pre‐sinusoidal and sinusoidal) and ...
Chalasani, Naga, Mathur, Karan, Pyko, Maximillian, Samala, Niharika, Vuppalanchi, Raj   +4 more
core   +1 more source