Results 81 to 90 of about 340,481 (262)

Heart Failure Monitoring System Based on Wearable and Information Technologies [PDF]

, 2007
In Europe, Cardiovascular Diseases (CVD) are the leading source of death, causing 45% of all deceases. Besides, Heart Failure, the paradigm of CVD, mainly affects people older than 65.
Arredondo Waldmeyer, Maria Teresa, Hoyo Barbolla, Eva del, Ottaviano, Manuel, Salvi, Dario, Villalba Mora, Elena   +4 more
core   +2 more sources

Seipin‐Mediated Lipid Droplet Formation in Cardiomyocytes Ameliorates Cardiac Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu, Junxia Zhang, Yusi Chen, Geng Shen, Yufei Han, Zihao Zhou, Jinxuan Chen, Xuya Kang, Huilin Qu, Jiaxin Duanmu, Haibao Shang, Yingjia Li, Wei Huang, Yan Zhang   +13 more
wiley   +1 more source

Nonalcoholic fatty liver disease and portal hypertension

Exploration of Medicine, 2020
Nonalcoholic fatty liver disease (NAFLD) is a substantial and growing problem worldwide and has become the second most common indication for liver transplantation as it may progress to cirrhosis and develop complications from portal hypertension ...
Marvin Ryou, Nicholas Stylopoulos, Gyorgy Baffy   +2 more
doaj   +1 more source

Hydraulic Model Study of Waller Creek Tunnel Project for the City of Austin, Texas [PDF]

, 2010
This report provides the results of a series of model tests designed to understand the fluid dynamics involved with the Waller Creek Tunnel.Waller Creek is centrally located within the City of Austin, Texas, and has one of the most densely developed ...
Gessler, Dan, Johansson, Andrew E., Lagumbay, Randy, Li, Songheng   +3 more
core   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

Pharmacological Modulation of Liver and Spleen Stiffness in a Cirrhotic Rat Model

Hepatic Medicine: Evidence and Research
Omar Elshaarawy,1– 3 Shami Hasan M Alquzi,1 Felix Piecha,1,4 Vanessa Rausch,1 Johannes Mueller,1 Sebastian Mueller1 1Center for Alcohol Research, University of Heidelberg, Heidelberg, BW, Germany; 2Department of Gastroenterology, Liver Unit, Liverpool ...
Elshaarawy O, Alquzi SHM, Piecha F, Rausch V, Mueller J, Mueller S   +5 more
doaj  

Antioxidant effect of N-acetylcysteine on prehepatic portal hypertensive gastropathy in rats

Annals of Hepatology, 2014
Background. Portal hypertension is a clinical syndrome associated with the development of a hyperdynamic circulation and gastroesophageal varices.Aim. To evaluate the antioxidant effect of N-acetylcysteine on portal hypertensive rats.Material and methods.
Francielli Licks, M.sc., Camila Marques, Cláudio Zetler, Maria I. Morgan Martins, Cláudio A. Marroni, Norma P. Marroni   +5 more
doaj   +1 more source

Nasal Mucosa‐Derived Extracellular Vesicles as a Systemic Antiaging Intervention

Advanced Science, EarlyView.
This study shows that nasal mucosa‐derived extracellular vesicles (nmEVs) exert systemic anti‐ageing effects in mice by restoring circadian rhythm, suppressing cellular senescence, and improving cognitive function. In aged human bone marrow mesenchymal stem cells, nmEVs reverse senescence‐associated phenotypes and reactivate core clock gene expression.
Wentao Shi, Lu Bian, Mengyuan Yu, Jun Wang, Mingzhu Gao, Liping Shen, Xiao Zhang, Zhiliang Huang, Hong Tang, Long Lv, Yunduan Que, Zengli Miao, Xuechao Wu, Qing Wang, Xiaojie Lu   +14 more
wiley   +1 more source

Double-Row Repair Technique for Bursal-Sided Partial-Thickness Rotator Cuff Tears [PDF]

, 2018
Rotator cuff pathology is a common cause of shoulder pain in the athletic and general population. Partial-thickness rotator cuff tears (PTRCT) are commonly encountered and can be bursal-sided, articular-sided, or intratendinous.
Carter, MD, Aaron, Freedman, Kevin, Salem, Hytham, Tjoumakaris, Fotios   +3 more
core   +2 more sources