Results 51 to 60 of about 24,071,321 (338)

Towards an Ontology Metadata Standard [PDF]

, 2006
In this poster, we present (i) a proposal for a metadata standard, known as Ontology Metadata Vocabulary (OMV) which is based on discussions in the EU IST thematic network of excellence Knowledge Web1 and (ii) two complementary reference implementations
Gómez-Pérez, A., Hartmann, J., Palma, R.   +2 more
core   +1 more source

Commissioning and Evaluation of an Electronic Portal Imaging Device-Based In-Vivo Dosimetry Software. [PDF]

, 2018
This study reports on our experience with the in-vivo dose verification software, EPIgray® (DOSIsoft, Cachan, France). After the initial commissioning process, clinical experiments on phantom treatments were evaluated to assess the level of accuracy of ...
Cheung, Joey, Held, Mareike, Husson, François, Morin, Olivier, Perez Andujar, Angelica   +4 more
core   +2 more sources

Pediatric patient portal use in one health system

J. Am. Medical Informatics Assoc., 2019
OBJECTIVE The study sought to assess, for children in one large health system, (1) characteristics of active users of the patient portal (≥1 use in prior 12 months), (2) portal use by adolescents, and (3) variations in pediatric patient portal use ...
P. Szilagyi, R. Valderrama, S. Vangala, Christina Albertin, David Okikawa, M. Sloyan, Nathalie Lopez, Carlos F. Lerner   +7 more
semanticscholar   +1 more source

The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology

Nature Cancer, 2022
There is a growing need for systems that efficiently support the work of medical teams at the precision-oncology point of care. Here, we present the implementation of the Molecular Tumor Board Portal (MTBP), an academic clinical decision support system ...
D. Tamborero, R. Dienstmann, M. Rachid, J. Boekel, A. López-Fernández, Markus Jonsson, A. Razzak, I. Braña, L. de Petris, J. Yachnin, Richard D. Baird, Y. Loriot, C. Massard, P. Martin-Romano, Frans L. Opdam, R. Schlenk, C. Vernieri, M. Masucci, X. Villalobos, Elena Chavarria, Shubha Danny Svetlana Richard Mariska Lennart Costanza Lu Anand Baars Bajalica-Lagercrantz Baird Bierkens Bl, S. Anand, Danny Baars, S. Bajalica-Lagercrantz, Richard D. Baird, M. Bierkens, L. Blomqvist, Costanza Bono, G. Doherty, Arnauld Forest, Valentina Fornerone, Paola Gabaldi, F. Haglund, J. Hartman, P. Horák, T. Jutzi, Mary A. Kasanicki, S. Kreutzfeldt, L. Le Cornet, R. Lewensohn, J. Lindberg, Carlos Lopez, Andreas Lundqvist, José-Ezequiel Martín, G. Meijer, S. Muñoz, M. N. Camus, C. Nicotra, P. Nuciforo, Petra Oberrauch, P. Östling, Laura Pelz, Alejandro Piris-Giménez, E. Provenzano, E. Rouleau, John Rowell, O. Saavedra, Giovanni Scoazec, K. Seamon, M. Tischkowitz, L. E. van der Kolk, Ruud van der Noll, M. Vieito, D. Vis, A. Vivancos, C. von Gertten, A. Wennborg, L. Wessels, V. Wirta, J. Balmaña, G. Apolone, C. Caldas, J. Bergh, I. Ernberg, S. Fröhling, E. Garralda, C. Karlsson, J. Tabernero, E. Voest, J. Rodón, J. Lehtiö   +80 more
semanticscholar   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

ChlamyCyc - a comprehensive database and web-portal centered on _Chlamydomonas reinhardtii_ [PDF]

, 2009
*Background* - The unicellular green alga _Chlamydomonas reinhardtii_ is an important eukaryotic model organism for the study of photosynthesis and growth, as well as flagella development and other cellular processes.
Dirk Walther, Jan-Ole Christian, Patrick May, Stefan Kempa   +3 more
core   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

IgA-codominant Post-streptococcal Glomerulonephritis in a Patient with Type 1b Abernethy Malformation: A New Insight into the Pathogenesis

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Post-streptococcal glomerulonephritis is an immune complex-mediated glomerulonephritis as a result of transient dysregulation of alternate complement pathway along with in situ immune complex formation.
Shashank M. Shivanna, Umesha Lingaraj, Kishan Aralapuram, Bhushan C. Shetty, C. G. Sreedhara   +4 more
doaj   +1 more source

Corporate Portal Management System [PDF]

, 2012
Web Portal Software Systems have become a very effective communication medium for sharing. Our Portal Management System dramatically simplifies the creation and management of portals.
Balakrishna, A. Guru, Gupta, Ankit, Nilagiri, Bhargav   +2 more
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source