Results 191 to 200 of about 956,003 (382)
Abstract Background Phosphorylated signal transducer and activator of transcription 3 (p‐STAT3) has emerged as a critical modulator of hepatocellular carcinoma (HCC) progression. However, its role in three‐dimensional (3D) chromatin conformation and the expression of genes linked to HCC aggressiveness remains largely unexplored.
Sunyoung Jang+9 more
wiley +1 more source
Prospective intraindividual comparison between respiratory-triggered balanced steady-state free precession and breath-hold gradient-echo and time-of-flight magnetic resonance imaging for assessment of portal and hepatic veins [PDF]
The purpose of this study was to compare respiratory-triggered balanced steady-state free precession (bSSFP) with breath-hold contrast-enhanced dynamic two-dimensional (2D) gradient-echo (GRE) and time-of-flight (TOF) magnetic resonance imaging (MRI) for
Göpfert, Kerstin+9 more
core
Several derivatives incorporating five‐membered aromatic rings are described in this review as bile acid receptor modulators, particularly targeting the farnesoid X receptor and the G protein‐coupled bile acid receptor 1. This review provides a comprehensive analysis of patents and literature that is useful to support researchers in the design of new ...
Claudia Finamore+5 more
wiley +1 more source
Abstract Imlunestrant (LY3484356) is a next‐generation orally bioavailable selective estrogen receptor degrader being investigated for the treatment of estrogen receptor–positive advanced breast and endometrial cancers. This Phase 1, open‐label, 2‐part study evaluated the disposition and absolute bioavailability of [14C]‐imlunestrant in 16 US‐based ...
Amita Datta‐Mannan+6 more
wiley +1 more source
A Phase 1, open‐label, single‐dose, fixed‐sequence crossover study utilizing a hybrid decentralized clinical trial (DCT) design with and without practice sessions for wearable devices and PK sampling was conducted in eight healthy participants. Using etrasimod, the study assessed the feasibility of conducting a Phase 1 hybrid DCT by the Pfizer Clinical
Bimal K. Malhotra+9 more
wiley +1 more source
On the Resorption of Glucose into the Portal Vein
YASUTARO SATAKÉ, IJURO FUJII
openalex +2 more sources
The Impact of Climate Change on the Performance of Agricultural Companies Worldwide
ABSTRACT This study examines the impact of climate change on agricultural firms, focusing on physical risks, both chronic (e.g., temperature and precipitation) and acute (e.g., droughts and floods). We conduct a panel data analysis of 19,929 companies in 69 countries across five continents from 2013 to 2021.
Karen Serrano+3 more
wiley +1 more source
The patient was a 43-year-old man with chronic hepatitis B without history of hepatocellular carcinoma (HCC), who was first diagnosed with thrombosis in right portal vein trunk and portal vein branches and ruptured esophageal varices in October 2011.
Masaya Saito+9 more
doaj
Amelioration of normothermic canine liver ischemia with prostacyclin. [PDF]
A model of hepatic ischemia was developed in dogs using a pump-driven splanchnic-to-jugular vein bypass during crossclamping of the portal triad. An LD50 was established with three hours of ischemia.
ChapChap, P+10 more
core
A NEW METHOD FOR CANNULATING THE PORTAL VEIN OF DOGS
A.E. Denton+2 more
openalex +1 more source