Results 91 to 100 of about 7,461,083 (331)

Hyperpolarization of [1‐13C]Ketoisocaproate‐d2 by Reversible Exchange with Parahydrogen Enables Profiling of Branched‐Chain‐Amino‐Acid Metabolism in Cellulo and in Vivo

Advanced Science, EarlyView.
We report the fast generation of biocompatible solutions of highly 13C‐hyperpolarized (≈11%) partially‐deuterated ketoisocaproate within <6 min using spin‐lock‐induced crossing and reversible exchange with parahydrogen (SLIC‐SABRE). This enables rapid detection of branched‐chain‐amino‐acid transferase 1 (BCAT1) protein expression and investigation of ...
Stefan Petersen, Philipp R. Groß, Paul M. Schmidt, Henri de Maissin, Asitan Rittinger, Robert Willing, Adriana Sacristán‐Martín, Lisa Heß, Jule Koch, Sebastian Lucas, Maxim Zaitsev, Dominik von Elverfeldt, Martin Grashei, Franz Schilling, Jan‐Bernd Hövener, André F. Martins, Max von Delius, Thomas Reinheckel, Andreas B. Schmidt   +18 more
wiley   +1 more source

Gray Wolf Optimization Algorithm for Multi-Constraints Second-Order Stochastic Dominance Portfolio Optimization

Algorithms, 2018
In the field of investment, how to construct a suitable portfolio based on historical data is still an important issue. The second-order stochastic dominant constraint is a branch of the stochastic dominant constraint theory.
Yixuan Ren, Tao Ye, Mengxing Huang, Siling Feng   +3 more
doaj   +1 more source

Exploiting Bulk Photovoltaic Effect in a Polar Hybrid Perovskite Towards Self‐Powered Detection of Weak Ultraviolet Polarized Light

Advanced Science, EarlyView.
Benefiting from intrinsic polarization, DJ‐type 2D perovskite crystals deliver self‐powered polarization‐resolved photocurrent under weak polarized UV light via the bulk photovoltaic effect, showing a high anisotropic factor of 8. ABSTRACT Weak light detection is essential for achieving high‐performance photodetectors with minimal power consumption ...
Xinyuan Zhang, Jianbo Wu, Wai‐Yeung Wong   +2 more
wiley   +1 more source

Portfolio Optimization by Using the Symbiotic Organisms Search [PDF]

تحقیقات مالی, 2016
The portfolio optimization has become one of the most important issues for the companies operating in the capital market. When the real-world conditions and restrictions, including cardinality constraint are considered in portfolio optimization, the ...
Emran Mohammadi, Seyed Erfan Mohammadi, Shahin Ramtinnia   +2 more
doaj   +1 more source

Credit portfolio optimization: A multi-objective genetic algorithm approach

, 2021
The algorithm for optimization of a credit portfolio has not been fully demonstrated. This paper fills the gap in the literature by presenting a general approach for optimizing a credit portfolio by minimizing the default risk of the entire portfolio ...
Zhi Wang, Xuan Zhang, Zhekai Zhang, Dachen Sheng   +3 more
semanticscholar   +1 more source

Chlorine‐Functionalized Silane‐Modified Copper Electrocatalyst for Enhanced CO2 Reduction to Multi‐Carbon Products

Advanced Science, EarlyView.
A chlorine‐functionalized silane modifier (CPTMS) is introduced to cooperatively regulate CO2 reduction to C2+ products on Cu‐based catalysts. Dual‐functional interface sequentially enhances CO2 activation, intermediates protonation and C─C coupling, delivering a 5‐fold increase in C2+ faradaic efficiency (FE, 75% vs.
Ying Ying Ch'ng, Sankhadip Saha, Ming Zhang, Shujie Zhou, Lixue Jiang, Putri Ramadhany, Jitraporn Vongsvivut, Adrian Cernescu, Priyank Vijaya Kumar, Yihao Shan, Zhipeng Ma, Xiaoxuan Luo, Rahman Daiyan, Zhaojun Han, Rose Amal   +14 more
wiley   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Beyond Probiotics: Postbiotics for Healthy Aquaculture

Advanced Science, EarlyView.
This critical review assesses limitations of probiotics and proposes postbiotics, preparations of inanimate microorganisms and their metabolites, as a more stable, controlled, and biosafe formulation. Postbiotics offer significant advantages during industrial aquafeed production and storage. However, their practical implementation is currently hindered
Michael Leonidas Chikindas, Delin Xu, Igor V. Popov, Kayque Ordonho Carneiro, Nilufar Arashovna Elova, Gullola Amirovna Bekmurodova, Dildora Amindjanovna Amirsaidova, Astghik Pepoyan, Shakhlo Mirjamalovna Miralimova, Oleg V. Mitrokhin, Liubov S. Sichel, John Tagg, Svetoslav Dimitrov Todorov   +12 more
wiley   +1 more source

ANALISIS PORTOFOLIO SAHAM LQ45 MENGGUNAKAN FUNGSI UTILITAS KUADRATIK

E-Jurnal Matematika, 2013
Utility function can use to give risk preference for investors who want to get the benefits gained meets investment targets. Quadratic utility functions on optimal portfolio is strongly influenced by the expected return and standard deviation.
KADEK FRISCA AYU DEVI, KOMANG DHARMAWAN, NI MADE ASIH   +2 more
doaj   +1 more source

Continuous Molecular Monitoring Using Electrochemical Aptamer‐Based Sensors: Remaining Challenges for Long‐Term In Vivo Deployment

Advanced Science, EarlyView.
Continuous molecular monitoring using electrochemical aptamer‐based sensors enables real‐time tracking of dynamic biomarkers with transformative potential for precision medicine. Achieving clinically relevant month‐long stability remains a central challenge due to multiple degradation pathways.
Shibo Liu, Xiangling Li, Wei Ouyang
wiley   +1 more source