Results 91 to 100 of about 482 (124)

An acidic phospholipase A₂ with antibacterial activity from Porthidium nasutum snake venom.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2012
Snake venoms are complex mixtures of proteins among which both basic and acidic phospholipases A(2) (PLA(2)s) can be found. Basic PLA(2)s are usually responsible for major toxic effects induced by snake venoms, while acidic PLA(2)s tend to have a lower toxicity.
Leidy Johana, Vargas, Mónica, Londoño, Juan Carlos, Quintana, Carolina, Rua, Cesar, Segura, Bruno, Lomonte, Vitelbina, Núñez   +6 more
openaire   +1 more source

Antitumor potential of Pllans-II, an acidic Asp49-PLA2 from Porthidium lansbergii lansbergii snake venom on human cervical carcinoma HeLa cells.

International Journal of Biological Macromolecules, 2019
This work shows for the first time the antitumoral and angiostatic potential effects of Pllans–II, an acidic monomeric Asp49–PLA2 from Porthidium lansbergii lansbergii snake venom on HeLa cells.
Eliécer Jiménez-Charris, D. Lopes, S. Gimenes, S. Teixeira, Leonel Montealegre-Sánchez, L. Solano-Redondo, Leonardo Fierro–Pérez, V. M. R. Rodrigues Ávila   +7 more
semanticscholar   +1 more source

Tailored toxins: Coagulotoxic variations in Atropoides, Cerrophidion, Metlapilcoatlus, and Porthidium viperid venoms against diverse vertebrate plasmas.

Toxicon
Venom is an adaptative trait that allows predators to subjugate prey. Despite this, there remains a distinct lack of research regarding the coagulotoxic effects of snake venom upon a species preferred prey.
L. Jones, E. Neri-Castro, Nicholas J. Youngman, J. Llinas, M. Haworth, Amber Gillett, Bryan G. Fry   +6 more
semanticscholar   +1 more source

Antitumoral Potential of Lansbermin-I, a Novel Disintegrin from Porthidium lansbergii lansbergii Venom on Breast Cancer Cells.

Current Topics in Medicinal Chemistry, 2019
BACKGROUND Disintegrins from snake venoms bind with high specificity cell surface integrins, which are important pharmacological targets associated with cancer development and progression.
Leonel Montealegre-Sánchez, S. Gimenes, D. Lopes, S. Teixeira, L. Solano-Redondo, Veridiana de M Rodrigues, Eliécer Jiménez-Charris   +6 more
semanticscholar   +1 more source

Ontogenetic Variation in Coagulotoxic Activity and Antivenom Efficacy of Central American Pit Viper Venoms (Cerrophidion, Metlapilcoatlus, Ophryacus and Porthidium).

Biochimie
Ontogenetic variation in venom activity and composition has been documented across several pit viper genera, but these toxicological variations poorly understood in Cerrophidion, Metlapilcoatlus, Ophryacus, and Porthidum.
L. Jones, E. Neri-Castro, Uri O. García-Vázquez, Bryan G. Fry   +3 more
semanticscholar   +1 more source

Purpura in serum sickness: a case of polyvalent snake antivenom reaction following Porthidium ophryomegas envenomation

Revista de Patologia Tropical / Journal of Tropical Pathology
This reports a case of a 68-year-old woman with a history of snake bite from Porthidium ophryomegas (commonly known as Tamagás Negro), treated with polyvalent snake antivenom.
Iván Daniel Pineda, J. Ruiz
semanticscholar   +1 more source

First records of Chelostoma nasutum, Trachusa laeviventris and Nomada trispinosa from Italy, with notes on Megachile rufescens in northwestern Italy

Bollettino della Società Entomologica Italiana
The bees Chelostoma nasutum, Trachusa laeviventris and Nomada trispinosa were collected for the first time in Italy. The occurrence of Megachile rufescens in northwestern Italy is discussed.
M. Bonifacino, Maurizio Cornalba, Sirio Gamba, Cristina Mantoni, Maurizio Mei   +4 more
semanticscholar   +1 more source

Proteomic profiling, functional characterization, and immunoneutralization of the venom of Porthidium porrasi, a pitviper endemic to Costa Rica.

Acta Tropica, 2019
The genus Porthidium includes nine pitviper species inhabiting Mexico, Central America, and northern South America. Porthidium porrasi is a species endemic to the Southwest of Costa Rica, for which no information on its venom was available. In this study,
Rebeca Méndez, F. Bonilla, M. Sasa, Quetzal Dwyer, Julián Fernández, B. Lomonte   +5 more
semanticscholar   +1 more source

Caracterización inmunoquímica y enzimática del veneno de la serpiente Porthidium nasutum

2021
Licenciado en Biología y Educación ...
openaire   +1 more source

EXTH-51. Snake venom bioprospecting as an approach to finding potential anti-glioblastoma molecules: evaluation of the antitumoral effect of the disintegrin lansbermin-I from the venom of the snake Porthidium lansbergii in tumor cell lines of Glioblastoma and non-tumorigenic astrocytic lines

Neuro-Oncology
We isolated for the first time Lansbermin-I, an RGD-type disintegrin, from the venom of the snake Porthidium lansbergii, obtained by HPLC and sequenced by mass spectrometry. We used T98G Glioblastoma(GB) cell line from ECACC.
Javier Orozco Mera, Eliécer Jiménez Charris, Á. Gómez, M. Sánchez   +3 more
semanticscholar   +1 more source