Results 111 to 120 of about 1,328,425 (260)
British Journal of Clinical Pharmacology, EarlyView.Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer +4 more
wiley +1 more source
Regulatory harmonization: Evolution, globalization and future directions
British Journal of Clinical Pharmacology, EarlyView.Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm +2 more
wiley +1 more source
Implementation and use of risk minimization control tools in the EU: A multistakeholder survey
British Journal of Clinical Pharmacology, EarlyView.Aims This study characterized stakeholders' experiences with national implementation of risk minimization control tools (RMCTs), such as healthcare professional qualification, healthcare facility accreditation and medical intervention prior to treatment initiation, for eight medicinal products across eight European Union countries. Methods We conducted
Sharon C. M. Essink +21 more
wiley +1 more source
Ceftriaxone‐associated immune haemolytic anaemia: A patient‐level systematic review
British Journal of Clinical Pharmacology, EarlyView.Abstract Ceftriaxone can cause acute haemolysis. Its clinical presentation, risk factors, and outcomes remain incompletely characterized. We conducted a systematic review of published cases with patient‐level data, following international guidelines and with registration in PROSPERO (CRD420261338709). Reports were identified through three bibliographic
Sonja Miotti +9 more
wiley +1 more source
Economic evaluations of antiobesity medications: A systematic literature review
British Journal of Clinical Pharmacology, EarlyView.The global prevalence of obesity is rising rapidly. With several antiobesity medications approved and many more in development, understanding their economic value is increasingly important. This study reviews full economic evaluations of approved antiobesity medications to assess cost‐effectiveness and inform reimbursement and access decisions.
Martina Jurković +5 more
wiley +1 more source
Towards appropriate guidance for the ethical challenges of environmentally sustainable prescribing
British Journal of Clinical Pharmacology, EarlyView.The environmental impact of medicines poses a significant threat to planetary and public health, making it essential to integrate environmental sustainability into prescribing practices. While the most effective measures to reduce environmental impact, such as reducing unnecessary prescriptions and medication waste, are consistent with appropriate ...
Joost D. Piët +22 more
wiley +1 more source
British Educational Research Journal, EarlyView.Abstract This article presents findings from an Australian study investigating the practices of middle leaders responsible for facilitating school development. Despite middle leaders being increasingly recognised as essential in the development of teaching and learning in schools, middle leadership remains under‐researched and comparatively overlooked ...
Peter Grootenboer +3 more
wiley +1 more source
‘I was treated as a deficit’: Immigrant teachers' career progression in Australia
British Educational Research Journal, EarlyView.Abstract Immigrant teachers have long been recruited through skilled and employer‐sponsored migration schemes to address teacher shortages in Australia, yet their career trajectories remain constrained by systemic inequities that limit their integration and professional development opportunities.
Ching Ting Tany Kwee +2 more
wiley +1 more source
British Educational Research Journal, EarlyView.Abstract Teacher retention is often explained through workload, job satisfaction and burnout, but these accounts have examined less systematically whether teachers experience their profession as socially and institutionally recognised. Drawing on recognition theory, this study examines how occupational recognition is configured across material and ...
Mengting Qian +3 more
wiley +1 more source