Results 91 to 100 of about 1,283,070 (258)

Repertórios léxicos hispano-lusos en los manuales de conversación de finales del siglo XIX y principios del XX

Linguarum Arena, 2019
This paper examines the lexical repertoires in Spanish and Portuguese that are included in two conversation manuals: O espanhol tal qual se fala. Novissima guía de conversação com a pronúncia figura, work elaborated for the Portuguese who want to ...
Nerea Fernández de Gobeo Díaz de Durana
doaj  

Von In‐Silico bis In‐Cerebro – Entwicklung des Orexinrezeptor Antagonisten „Photorexant“ zur Photomodulation In Vitro und im Gehirn der Maus

Angewandte Chemie, EarlyView.
Durch einen strukturbasierten Designansatz wurden photoschaltbare Derivate des von der FDA zugelassenen Arzneistoffes Suvorexant entwickelt, gedockt, synthetisiert und pharmakologisch an den Orexin‐1‐ und 2‐Rezeptoren (OX1R und OX2R) charakterisiert.
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

Portekizli'lerle Kızıldeniz'de Mücadele ve Hicaz'da Osmanlı Hâkimiyetinin Yerleşmesi Hakkında Bir Vesika

Belgeler, 1965
Kızıldeniz tarafından birdenbire Portekizlilerin taarruzu karşısında şaşalayan Memlük Sultanı, ister istemez Osmanlı sultanına müracaat ettiği zaman, Osmanlıların İslam alemi içinde yerini resmen itiraf etmiş oluyordu.
M. Yakub Mughul
doaj  

Neoadjuvant therapy in rectal cancer—one year follow-up results of standard versus total neoadjuvant strategies

World Journal of Surgical Oncology
Background Locally advanced rectal cancer (LARC) poses a significantly challenge in clinical management, requiring a multimodal treatment approach.
Luís Correia Gomes, Bernardo Alves Pereira, Isália Miguel, Ana Luís, Ana Pina, Cátia Pedro, Daniela Cavadas, Daniela Pereira, Joana Lemos, João Maciel, João Oliveira, José Venâncio, Madalena Santos, Manuel Limbert, Miguel Braga, Miriam Abdulrehman, Pedro Freitas, Ricardo Fonseca, Teresa Ferreira, Isadora Rosa   +19 more
doaj   +1 more source

Respiratory syncytial virus vaccination in older adults and patients with chronic disorders: A position paper from the Portuguese Society of Pulmonology, the Portuguese Association of General and Family Medicine, the Portuguese Society of Cardiology, the Portuguese Society of Infectious Diseases and Clinical Microbiology, the Portuguese Society of Endocrinology, Diabetes and Metabolism, and the Portuguese Society of Internal Medicine

Pulmonology
Background Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract infection, hospitalisation and death in adults.Methods Based on evidence regarding the impact of RSV on adult populations at risk for severe infection and the ...
Tiago Alfaro, Filipe Froes, Cláudia Vicente, Rui Costa, Cristina Gavina, Rui Baptista, António Maio, Saraiva da Cunha, João Sérgio Neves, Pedro Leuschner, Sofia Duque, Paula Pinto   +11 more
doaj   +1 more source

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

Angewandte Chemie International Edition, EarlyView.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

Sustainable Manufacturing Platforms for Closed‐Cycle Bioeconomy Applications

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The transition to a circular bioeconomy requires innovative production platforms that prioritize sustainability, resource efficiency, and waste minimization. Organic waste from agriculture, aquaculture, and food production represents an underutilized feedstock for biomanufacturing, contributing to a circular economy.
Yelizaveta Chernysh, Ruslan Ostroha, Hynek Roubík   +2 more
wiley   +1 more source

A High-Quality Underwater Acoustic Dataset for Algorithm Development and Analysis

Scientific Data
As data becomes increasingly available, relying on quality datasets for algorithm analysis and development is essential. However, data gathering can be expensive and time-consuming, and this process must be optimized to allow others to reuse data with ...
Victor Lobo, Nuno Pessanha Santos, Ricardo Moura   +2 more
doaj   +1 more source

Cooling Holes in Polymer Spur Gears: A Critical Analysis of Heat Dissipation Benefits and Mesh Stiffness Penalties

Journal of Applied Polymer Science, EarlyView.
Cooling holes provide a simple passive cooling strategy for polymer spur gears, reducing maximum operating temperature by up to 9.39% while introducing a measurable gear mesh stiffness penalty. A validated response‐surface model reveals how hole size and location govern this thermal–mechanical trade‐off, enabling design optimization for thermally and ...
Abderrahim Baccar, Ahmed Samet, Ahmed Hammami, Nuno Dourado, Ali Akrout, Mohamed Haddar   +5 more
wiley   +1 more source

Origin, evolution and biogeographic dynamics of the European rabbit (Oryctolagus cuniculus) in Southwestern Europe

The Anatomical Record, EarlyView.
Abstract The Pleistocene is a key period for understanding the evolutionary history and palaeobiogeography of the European rabbit (Oryctolagus cuniculus). The species was first documented in southeastern Iberia at the beginning of the Middle Pleistocene and appears to have rapidly spread throughout Southwestern Europe, where it was found in numerous ...
Maxime Pelletier
wiley   +1 more source