Results 61 to 70 of about 2,455,369 (286)
Advanced Science, EarlyView.Although the tumor microenvironment is known to shape immunotherapy response, its key determinants remain elusive, underscoring the critical need for single‐cell resolution analytical frameworks. We present scResponse, an efficient algorithm to quantify single‐cell responses to immunotherapy. By capturing diverse cellular subtypes and states associated
Qi Dong +21 more
wiley +1 more source
Advanced Science, EarlyView.Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li +13 more
wiley +1 more source
MEASUREMENT FOR ACCEPTANCE OF SUPPLY CHAIN SIMULATOR APPLICATION USING TECHNOLOGY ACCEPTANCE MODEL [PDF]
Russian Journal of Agricultural and Socio-Economic Sciences, 2018 The aim of this research for was to measure the user acceptance of simulator application which was built as a tool for student in learning of supply chain, particularly in bullwhip effect problem.
Mulyati E., Hamidin D., Fauzan M.N.
doaj +1 more source
The Moment Problem for Continuous Positive Semidefinite Linear functionals
, 2012 Let $\tau$ be a locally convex topology on the countable dimensional polynomial $\reals$-algebra $\rx:=\reals[X_1,...,X_n]$. Let $K$ be a closed subset of $\reals^n$, and let $M:=M_{\{g_1, ... g_s\}}$ be a finitely generated quadratic module in $\rx$. We
C. Berg +12 more
core +1 more source
Aging and Electrical Stability of DNTT Honey‐Gated OFETs
Advanced Electronic Materials, EarlyView.DNTT honey‐gated organic transistors were fabricated and evaluated to assess short‐ and long‐term stability under electrical stress and aging. Short‐term transfer measurements (five days, 40 sweeps/day) showed minimal parameter shift, while extended measurements revealed gradual degradation over weeks.
Douglas H. Vieira +8 more
wiley +1 more source
Microtubule motors transport phagosomes in the RPE, and lack of KLC1 leads to AMD-like pathogenesis. [PDF]
, 2015 The degradation of phagosomes, derived from the ingestion of photoreceptor outer segment (POS) disk membranes, is a major role of the retinal pigment epithelium (RPE). Here, POS phagosomes were observed to associate with myosin-7a, and then kinesin-1, as
Diemer, Tanja +6 more
core +1 more source
Quantum chaos with non-periodic, complex orbits in the Resonant Tunneling Diode
, 1998 We show that a special type of orbits, which are non-periodic and complex, 'Saddle Orbits' (SOs) describe accurately the quantal and experimental current oscillations in the Resonant Tunneling Diode in tilted fields.
Monteiro, T. S., Saraga, D. S.
core +1 more source
Advanced Intelligent Discovery, EarlyView.This study integrates random matrix theory (RMT) and principal component analysis (PCA) to improve the identification of correlated regions in HIV protein sequences for vaccine design. PCA validation enhances the reliability of RMT‐derived correlations, particularly in small‐sample, high‐dimensional datasets, enabling more accurate detection of ...
Mariyam Siddiqah +3 more
wiley +1 more source
POS Tagging and its Applications for Mathematics
, 2014 Content analysis of scientific publications is a nontrivial task, but a useful and important one for scientific information services. In the Gutenberg era it was a domain of human experts; in the digital age many machine-based methods, e.g., graph ...
J.C. Platt, T.D. Nguyen, U. Schöneberg
core +1 more source
Advanced Intelligent Discovery, EarlyView.The authors develop a deep learning model for real‐time tracking of wound progression. The deep learning framework maps the nonlinear evolution of a time series of images to a latent space, where they learn a linear representation of the dynamics. The linear model is interpretable and suitable for applications in feedback control.
Fan Lu +11 more
wiley +1 more source