Results 41 to 50 of about 27,357 (215)
Frontiers in Pharmacology, 2022 The present study explored the effects of posaconazole on tacrolimus population pharmacokinetics (PPK) in children with Crohn’s disease (CD) undergoing hematopoietic stem cell transplantation (HSCT).
Xiao Chen +8 more
doaj +1 more source
Posaconazole Tablet Pharmacokinetics: Lack of Effect of Concomitant Medications Altering Gastric pH and Gastric Motility in Healthy Subjects. [PDF]
, 2014 Posaconazole oral suspension is an extended-spectrum triazole that should be taken with food to maximize absorption. A new posaconazole tablet formulation has demonstrated improved bioavailability over the oral suspension in healthy adults in a fasting ...
Chang, Peter S. +5 more
core +2 more sources
Annals of Hematology, 2020 With the advent of new targeted drugs in hematology and oncology patient prognosis is improved. Combination with antifungal prophylaxis challenges clinicians due to pharmacological profiles prone to drug–drug interactions (DDI).
J. Stemler +4 more
semanticscholar +1 more source
Haematologica, 2012 Background Posaconazole is effective as primary antifungal prophylaxis of invasive fungal diseases in patients with acute myeloid leukemia.Design and Methods The impact of primary antifungal prophylaxis administered during front-line chemotherapy for ...
Corrado Girmenia +14 more
doaj +1 more source
Lateral Flow Assays for the Diagnosis of Invasive Aspergillosis: Current Status. [PDF]
, 2017 Purpose of reviewDiagnosis during early stages of invasive aspergillosis (IA) and targeted antifungal treatment has the potential to improve survival significantly.
Heldt, Sven, Hoenigl, Martin
core +1 more source
BMC Infectious Diseases, 2018 Background Posaconazole therapeutic drug monitoring (TDM) is increasingly used in clinical practice. However, the utility of posaconazole TDM and the target of posaconazole plasma concentration for clinical successful prophylaxis remain uncertain and ...
Lu Chen +7 more
doaj +1 more source
Unravelling drug-induced hypertension: Molecular mechanisms of aldosterone-independent mineralocorticoid receptor activation by posaconazole [PDF]
, 2018 Drug-induced hypertension offers the opportunity to further understand pathways involved in the regulation of blood pressure. Posaconazole is an antifungal agent known to induce hypertension and hypokalaemia.
Ortiz, Alberto +1 more
core +2 more sources
Journal of Investigative Medicine High Impact Case Reports, 2017 Posaconazole is a commonly used medication for antifungal prophylaxis in patients with high-risk acute leukemia, such as acute myeloid leukemia. Despite clinical data that show that posaconazole is superior to other antifungal prophylaxis medications ...
Mayur D. Mody MD +3 more
doaj +1 more source
Posaconazole treatment of refractory coccidioidomycosis in dogs
Journal of Veterinary Internal Medicine, 2021 Background The majority of dogs with coccidioidomycosis recover with administration of fluconazole or itraconazole, although some cases are refractory or the dogs do not tolerate administration of these medications.
Lisa F. Shubitz +4 more
doaj +1 more source
Clinical Pharmacokinetics and Dose Recommendations for Posaconazole in Infants and Children. [PDF]
, 2018 OBJECTIVES: The objectives of this study were to investigate the population pharmacokinetics of posaconazole in immunocompromised children, evaluate the influence of patient characteristics on posaconazole exposure and perform simulations to recommend ...
A Moton +51 more
core +2 more sources