Results 1 to 10 of about 25,862 (171)
Antibiotics, 2023 (1) Background: To explore the impact of the degree of inflammation on voriconazole exposure in critically ill patients affected by COVID-associated pulmonary aspergillosis (CAPA); (2) Methods: Critically ill patients receiving TDM-guided voriconazole ...
Milo Gatti +6 more
doaj +1 more source
Scientific Reports, 2023 Posaconazole and voriconazole are commonly used for preventing invasive fungal disease (IFD), but few studies compared posaconazole with voriconazole for primary antifungal prophylaxis (PAP) in pediatric acute leukemia.
Songji Tu +5 more
doaj +1 more source
The pharmacokinetics of voriconazole [PDF]
British Journal of Clinical Pharmacology, 2003 Voriconazole (Vfend® Pfizer Global Research and Development, Sandwich, Kent, UK) is a broad-spectrum antifungal triazole that is structurally related to fluconazole. As with all triazole antifungal agents, voriconazole works principally by inhibition of cytochrome P450 14-α-demethylase (P450 14DM) [1, 2].
openaire +2 more sources
BMC Veterinary Research, 2020 Background Keratomycosis is a relatively common, sight threatening condition in horses, where treatment is often prolonged and costly. Subconjunctival (SCo) injections offer less resistance to drug diffusion than the topical route, resulting in better ...
Mariano Mora-Pereira +7 more
doaj +1 more source
Journal of Research in Pharmacy Practice, 2017 Objective: Voriconazole as a triazole antifungal agent is widely used for prophylaxis or treatment of fungal infections in allogeneic hematopoietic stem cell transplantation (HSCT).
Hamidreza Taghvaye Masoumi +3 more
doaj +1 more source
Clinical and Translational Science, 2021 Voriconazole is the mainstay for the treatment of invasive fungal infections in patients who underwent a kidney transplant. Variant CYP2C19 alleles, hepatic function, and concomitant medications are directly involved in the metabolism of voriconazole ...
Yi‐Chang Zhao +9 more
doaj +1 more source
Therapeutic Drug Monitoring of Sputum Voriconazole in Pulmonary Aspergillosis
Pharmaceutics, 2022 Voriconazole is one of the most used antifungal azoles against pulmonary aspergillosis. Therapeutic drug monitoring (TDM) of the voriconazole concentration in plasma is recommended in clinical practice guidelines to prevent treatment failure and toxicity.
Sacha Sarfati +7 more
doaj +1 more source
Frontiers in Pharmacology, 2022 Aims: We aimed to assess the impact of extracorporeal membrane oxygenation (ECMO) on voriconazole exposure.Methods: Adult critically ill patients with or without ECMO support receiving intravenous voriconazole therapy were included in this retrospective ...
Qinghua Ye +11 more
doaj +1 more source
Case Reports in Medicine, 2010 Voriconazole is a treatment for severe fungal infections. Prolonged voriconazole therapy may induce skin reactions, with 1% of severe photosensitivity accidents. Recently the imputability of voriconazole in skin carcinogenesis has been suggested.
C. Morice +6 more
doaj +1 more source
Voriconazole-induced arthritis, enthesitis and periostitis
Proceedings of Singapore Healthcare, 2023 Voriconazole is a fluoride-containing anti-fungal. Prolonged exposure can result in fluoride deposition within the bone extracellular matrix, resulting in periostitis and arthritis.
Adrian Mark Masnammany +3 more
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