Results 21 to 30 of about 43,404 (216)

Sustained-release voriconazole-thermogel for subconjunctival injection in horses: ocular toxicity and in-vivo studies

BMC Veterinary Research, 2020
Background Keratomycosis is a relatively common, sight threatening condition in horses, where treatment is often prolonged and costly. Subconjunctival (SCo) injections offer less resistance to drug diffusion than the topical route, resulting in better ...
Mariano Mora-Pereira, Eva M. Abarca, Sue Duran, William Ravis, Richard J. McMullen, Britta M. Fischer, Yann-Huei Phillip Lee, Anne A. Wooldridge   +7 more
doaj   +1 more source

Therapeutic Drug Monitoring of Sputum Voriconazole in Pulmonary Aspergillosis

Pharmaceutics, 2022
Voriconazole is one of the most used antifungal azoles against pulmonary aspergillosis. Therapeutic drug monitoring (TDM) of the voriconazole concentration in plasma is recommended in clinical practice guidelines to prevent treatment failure and toxicity.
Sacha Sarfati, Julien Wils, Timothée Lambert, Céline Mory, Laurent Imbert, Gilles Gargala, Hélène Morisse-Pradier, Fabien Lamoureux   +7 more
doaj   +1 more source

Combined Effect of CYP2C19 Genetic Polymorphisms and C-Reactive Protein on Voriconazole Exposure and Dosing in Immunocompromised Children

Frontiers in Pediatrics, 2022
BackgroundPediatric patients have significant interindividual variability in voriconazole exposure. The aim of the study was to identify factors associated with voriconazole concentrations and dose requirements to achieve therapeutic concentrations in ...
Juan Chen, Ying Wu, Yuelin He, Xiaoqin Feng, Yuqiong Ren, Shiting Liu   +5 more
doaj   +1 more source

Bloodstream yeast infections: a 15-month survey [PDF]

, 2009
A 15-month survey of 412 bloodstream yeast isolates from 54 Belgian hospitals was undertaken. Candida albicans was the most common species (47.3%) followed by C. glabrata (25.7%), C. parapsilosis (8.0%), C. tropicalis (6.8%) and Saccharomyces cerevisiae (
Detandt, M, Nolard, N, Swinne, D, Van Rooij, Pascale   +3 more
core   +1 more source

Predictors of Adverse Events and Determinants of the Voriconazole Trough Concentration in Kidney Transplantation Recipients

Clinical and Translational Science, 2021
Voriconazole is the mainstay for the treatment of invasive fungal infections in patients who underwent a kidney transplant. Variant CYP2C19 alleles, hepatic function, and concomitant medications are directly involved in the metabolism of voriconazole ...
Yi‐Chang Zhao, Xiao‐Bin Lin, Bi‐Kui Zhang, Yi‐wen Xiao, Ping Xu, Feng Wang, Da‐Xiong Xiang, Xu‐Biao Xie, Feng‐Hua Peng, Miao Yan   +9 more
doaj   +1 more source

Intracranial fusarium fungal abscess in an immunocompetent patient: case report and review of the literature. [PDF]

, 2014
Introduction Fusarium spp is an omnipresent fungal species that may lead to fatal infections in immunocompromised populations. Spontaneous intracranial infection by Fusarium spp in immunocompetent individuals is exceedingly rare.
Cadden, Joseph, Commins, Deborah, Giannotta, Steven L, Lee, Brian, Peterson, Asa, Pham, Martin H, Zada, Gabriel   +6 more
core   +1 more source

Evaluation of the interaction of intravenous and oral voriconazole with oral cyclosporine in iranian HSCT patients

Journal of Research in Pharmacy Practice, 2017
Objective: Voriconazole as a triazole antifungal agent is widely used for prophylaxis or treatment of fungal infections in allogeneic hematopoietic stem cell transplantation (HSCT).
Hamidreza Taghvaye Masoumi, Molouk Hadjibabaie, Mohammad Vaezi, Ardeshir Ghavamzadeh   +3 more
doaj   +1 more source

Medication Complications in Extracorporeal Membrane Oxygenation. [PDF]

, 2017
The need for extracorporeal membrane oxygenation (ECMO) therapy is a marker of disease severity for which multiple medications are required. The therapy causes physiologic changes that impact drug pharmacokinetics.
Aebi, Ami G. Shah, Anderson, Arlt, Barr, Barthelemy, Beiderlinden, Bein, Bembea, Bhatt-Meht, Boucher, Brandi N. Thoma, Brown, Buck, Buscher, Chung, Dagan, Dagan, de Montmollin, De Rosa, DeGrado, Donadello, Donadello, Dzierba, Erstad, Esper, Eyler, Flordelis Lasierra, Glauber, Greenberg, Gélisse, Hadidi, Hertzog, Hraiech, Hynynen, Johnston, Kawada, Kim, Koster, Krueger, Lamarche, Latronico, Lemaitre, Levison, Malfertheiner, Mehta, Michelle Peahota, Moore, Mousavi, Mulla, Mulla, Muntean, Oliver, Paden, Park, Perkins, Peters, Pettignano, Phillips, Pieri, Potter, Preston, Protti, Ranucci, Riker, Roberts, Roos, Rosen, Ruiz, Rybak, Saini, Sanfilippo, Satyapriya, Schmith, Shekar, Shekar, Shekar, Shekar, Shekar, Sherwin, Sklar, Smith, Spriet, Staudacher, Strunk, Subramaniam, Szefner, Tellor, Trudzinski, Tulman, Turner, Veinstein, Vilay, Wagner, Walter K. Kraft, Welsch, Wen, Wildschut, Wu, Young   +99 more
core   +2 more sources

Multifocal Aggressive Squamous Cell Carcinomas Induced by Prolonged Voriconazole Therapy: A Case Report

Case Reports in Medicine, 2010
Voriconazole is a treatment for severe fungal infections. Prolonged voriconazole therapy may induce skin reactions, with 1% of severe photosensitivity accidents. Recently the imputability of voriconazole in skin carcinogenesis has been suggested.
C. Morice, A. Acher, N. Soufir, M. Michel, F. Comoz, D. Leroy, L. Verneuil   +6 more
doaj   +1 more source

Two cases of fungal keratitis caused by Metarhizium anisopliae [PDF]

, 2018
We present two cases of keratitis due to Metarhizium anisopliae in geographically separated areas of the United States. The isolates were microscopically similar but morphologically different and were identified by ribosomal DNA sequencing. Both isolates
Burd, Eileen M, Burnham, Carey-Ann D, Goodman, Abigail L, Lockhart, Shawn R, Lysen, Colleen B, Westblade, Lars F   +5 more
core   +2 more sources