Results 31 to 40 of about 25,647 (169)

Multifocal Aggressive Squamous Cell Carcinomas Induced by Prolonged Voriconazole Therapy: A Case Report

open access: yesCase Reports in Medicine, 2010
Voriconazole is a treatment for severe fungal infections. Prolonged voriconazole therapy may induce skin reactions, with 1% of severe photosensitivity accidents. Recently the imputability of voriconazole in skin carcinogenesis has been suggested.
C. Morice   +6 more
doaj   +1 more source

Impact of extracorporeal membrane oxygenation on voriconazole plasma concentrations: A retrospective study

open access: yesFrontiers in Pharmacology, 2022
Aims: We aimed to assess the impact of extracorporeal membrane oxygenation (ECMO) on voriconazole exposure.Methods: Adult critically ill patients with or without ECMO support receiving intravenous voriconazole therapy were included in this retrospective ...
Qinghua Ye   +11 more
doaj   +1 more source

Voriconazole-induced arthritis, enthesitis and periostitis

open access: yesProceedings of Singapore Healthcare, 2023
Voriconazole is a fluoride-containing anti-fungal. Prolonged exposure can result in fluoride deposition within the bone extracellular matrix, resulting in periostitis and arthritis.
Adrian Mark Masnammany   +3 more
doaj   +1 more source

Drug reservoir function of voriconazole impregnated human amniotic membrane: An in vitro study

open access: yesIndian Journal of Ophthalmology, 2021
Purpose: Earlier our group has demonstrated the drug reservoir function of the human amniotic membrane (HAM) using stable moxifloxacin and fortified cefazolin ophthalmic formulations and found it as a suitable tool to deliver drugs for an extended ...
Manali Hazarika   +2 more
doaj   +1 more source

Voriconazole and the liver

open access: yesWorld Journal of Hepatology, 2015
Voriconazole is an azole useful for the prophylaxis and the treatment of aspergillosis and other fungal infections in immunosuppressed subjects, as those found in aplasia after aggressive polychemotherapy treatments, after hematopoietic stem cell, liver or lung transplantation.
openaire   +2 more sources

Efficacy of voriconazole on leishmaniasis by Leishmania major: An in vitro and in vivo study

open access: yesAsian Pacific Journal of Tropical Medicine, 2018
Objective: To appraise the activity of voriconazole against Leishmania major (L. major) in vitro and its effectiveness on wound regeneration in cutaneous leishmaniasis in BALB/c mice.
Ahmad Oryan   +2 more
doaj   +1 more source

A rare case of voriconazole-induced vertebral periostitis in a patient with invasive aspergillus spondylodiscitis

open access: yesIndian Spine Journal, 2022
The author illustrates the first ever reported case of voriconazole-induced periostitis of vertebral body. A 66-year-old immunocompetent male patient was diagnosed with multilevel invasive aspergillus spondylodiscitis of dorsal spine and was put on long ...
Alok Jain   +3 more
doaj   +1 more source

In-vitro Antifungal Activities of Kombucha Tea Culture Supernatant Combined with Voriconazole against Vulvovaginal Candidiasis Clinical Isolates

open access: yesJournal of Health Science and Medical Research (JHSMR), 2023
Objective: To investigate the antifungal activity of voriconazole, with and without Kombucha tea culture, against Candida strains isolated from vulvovaginal candidiasis.  Material and Methods: The study included 150 females, within child-bearing periods,
Rasha H. Bassyouni   +7 more
doaj   +1 more source

Inflammation‐driven variability in drug metabolism: Insights from voriconazole treatment of HSCT recipients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Voriconazole is commonly used to prevent fungal infections after haematopoietic stem cell transplantation (HSCT). Although its metabolism is influenced by CYP2C19 genetics and inflammation, their combined effect is rarely considered in clinical practice, and integrated analyses remain limited.
Sylvia D. Klomp   +6 more
wiley   +1 more source

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup   +2 more
wiley   +1 more source

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