Results 91 to 100 of about 4,103,128 (288)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Least square-based vehicle position estimation algorithm

Tongxin xuebao, 2010
A vehicle position estimation algorithm base on least square optimization was prposed.Firstly,the algorithm deduced the convex constraint condition which the distance matrix had to conform within a short time interval.Then,the least square method was ...
PENG Xin, LI Ren-fa, YANG Liu, LIU Liang-jiao   +3 more
doaj  

UAV-Carried Multi-Sensor System for Detecting People and Monitoring Vital Signs in Open-Field Rescue Scenarios

IEEE Access
In post-disaster situations, emergency services require an efficient method to quickly detect and monitor the vital signs of injured people. In this work, we present a UAV-carried sensor system to locate injured people in open-field rescue scenarios and ...
Bassam Elmakhzangy, Philipp Stockel, Dascha Karelina, Patrick Wallrath, Sandra Nowok, Gunnar Briese, Reinhold Herschel, Nils Pohl, Christophe Maufroy, Stefan Sammito, Kai Kehe, Urs Schneider, Marco Huber   +12 more
doaj   +1 more source

Estimates of positive contractions [PDF]

Pacific Journal of Mathematics, 1969
Chacon, R. V., McGrath, S. A.
openaire   +3 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Improvement of Position Estimation Accuracy Using Multiple Access Points in Terminal Position Estimation based on Position Fingerprint [PDF]

, 2020
-In this paper, we consider a position estimation method based on position fingerprint of radio propagation characteristics. We propose a new method where multiple Access Points (APs) are used to improve the estimation performance.

core  

A Global Position Estimation Algorithm for Multi-Camera Multi-Object Tracking

IEEE Access
Traditional projection-based multi-camera multi-object tracking approaches typically project the bottom points of detected objects, such as feet, onto the ground plane to estimate global positions.
Dongjin Lee, Jungsu Yun, Hyunbean Yi
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source