Results 41 to 50 of about 59,238 (279)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Topological Defects, Orientational Order, and Depinning of the Electron Solid in a Random Potential

, 1994
We report on the results of molecular dynamics simulation (MD) studies of the classical two-dimensional electron crystal in the presence disorder. Our study is motivated by recent experiments on this system in modulation doped semiconductor systems in ...
A. Brass, A.B. Dzyubenko, A.C. Shi, C.A. Murray, C.C. Grimes, D. R. Nelson, D.R. Nelson, D.R. Nelson, D.S. Fisher, E.P. Wigner, F.I.B. Williams, F.R.N. Nabarro, G. Gruner, H. A. Fertig, H. Fukuyama, H.A. Fertig, H.J. Jensen, H.J. Jensen, H.W. Jiang, H.W. Jiang, H.W. Jiang, I.M. Ruzin, J.M. Kosterlitz, K. Maki, K. Strandburg, L. Bonsall, M. C. Cha, M.P. Allen, Min-Chul Cha, N.D. Mermin, P.A. Lee, R. Balescu, R. Dingle, R.C. Gann, R.L. Willett, S.N. Coppersmith, V.J. Goldman, V.M. Pudalov, Y. Imry, Y.P. Li   +39 more
core   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Modulated Memory Network for Video Object Segmentation

Mathematics
Existing video object segmentation (VOS) methods based on matching techniques commonly employ a reference set comprising historical segmented frames, referred to as ‘memory frames’, to facilitate the segmentation process.
Hannan Lu, Zixian Guo, Wangmeng Zuo
doaj   +1 more source

Three-Axis Pneumatic Haptic Display for the Mechanical and Thermal Stimulation of a Human Finger Pad

Actuators, 2021
Haptic displays have been developed to provide operators with rich tactile information using simple structures. In this study, a three-axis tactile actuator capable of thermal display was developed to deliver tactile senses more realistically and ...
Eun-Hyuk Lee, Sang-Hoon Kim, Kwang-Seok Yun   +2 more
doaj   +1 more source

X-ray spectrum of a pinned charge density wave

, 2004
We calculate the X-ray diffraction spectrum produced by a pinned charge density wave (CDW). The signature of the presence of a CDW consists of two satellite peaks, asymmetric as a consequence of disorder.
A. Guiner, Alberto Rosso, G. Grüner, K. B. Efetov, P. Le Doussal, S. Ravy, S. Rouzière, T. Giamarchi, Thierry Giamarchi   +8 more
core   +2 more sources

Flexibility and Dynamicity Enhances and Controls Supramolecular Self‐Assembly of Zinc(II) Metallogels

Advanced Functional Materials, EarlyView.
Zinc(II) coordination complexes with tunable aryloxy‐imine ligands exhibit controllable supramolecular self‐assembly into hierarchical fibrous structures. Coordination‐driven stacking, not π–π interactions, enables gelation, dynamic assembly/disassembly, and enhanced nanomechanical properties.
Merlin R. Stühler, Hesam Makki, Dorothee Silbernagl, Mathias Dimde, Kai Ludwig, Bengt E. Tegner, Christopher Greve, Konstantin Rausch, Eva M. Herzig, Anna Köhler, Alex J. Plajer   +10 more
wiley   +1 more source

Bond Orientational Order, Molecular Motion and Free Energy of High Density DNA Mesophases

, 1995
By equilibrating condensed DNA arrays against reservoirs of known osmotic stress and examining them with several structural probes, it has been possible to achieve a detailed thermodynamic and structural characterization of the change between two ...
Gawrisch, K., Parsegian, V. A., Podgornik, R., Rau, D. C., Rupprecht, A., Strey, H. H.   +5 more
core   +2 more sources

Multicolor Optoelectronic Synapse Enabled by Photon‐Modulated Remote Doping in Solution‐Processed Van Der Waals Heterostructures

Advanced Functional Materials, EarlyView.
Multicolor optoelectronic synapses are realized by vertically integrating solution‐processed MoS2 thin‐film and SWCNT. The electronically disconnected but interactive MoS2 enables photon‐modulated remote doping, producing a bi‐directional photoresponse.
Jihyun Kim, Hyunbin Kim, Gang Jin Cheon, Dohyun Lee, In Soo Kim, Uiyeon Won, Jongseok Lee, Sang Min Won, Joohoon Kang   +8 more
wiley   +1 more source

Positional information modulates transient regeneration-activated cell states during vertebrate appendage regeneration

iScience
Summary: Injury is common in the life of organisms. Because the extent of damage cannot be predicted, injured organisms must determine how much tissue needs to be restored.
Augusto Ortega Granillo, Daniel Zamora, Robert R. Schnittker, Allison R. Scott, Alessia Spluga, Jonathon Russell, Carolyn E. Brewster, Eric J. Ross, Daniel A. Acheampong, Ning Zhang, Kevin Ferro, Jason A. Morrison, Boris Y. Rubinstein, Anoja G. Perera, Wei Wang, Alejandro Sánchez Alvarado   +15 more
doaj   +1 more source