Results 131 to 140 of about 5,719,399 (328)

Two-Line Element Outlier and Space Event Detection Method Based on Multi-Strategy Genetic Algorithm

open access: yesApplied Sciences
The detection of two-line element (TLE) outliers and space events play a crucial role in enhancing spatial situational awareness. Therefore, this paper addresses the issue of TLE outlier detection methods that often overlook the mutual influence of ...
Haoyue Zhang, Chunmei Zhao, Zhengbin He
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Reprocessing of three-decade GNSS observations: millimeter-level nonlinear terrestrial reference frame, global velocity field and plate motion model refinement

open access: yesGeo-spatial Information Science
The Terrestrial Reference Frame (TRF) is essential for solid Earth research, including geodesy and geodynamics, providing a unified spatiotemporal datum.
Hu Wang   +6 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

A survey of GNSS receiver autonomous integrity monitoring: Research status and opportunities

open access: yesFrontiers in Physics
Integrity monitoring is crucial in applications closely related to the safety of human life and property, such as aviation, maritime navigation, autonomous driving, and rail transportation.
Zhen Huang   +10 more
doaj   +1 more source

Prone positioning in severe acute respiratory distress syndrome.

open access: yesNew England Journal of Medicine, 2013
C. Guérin   +25 more
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

CHULA: Custom Heuristic Uncertainty-Guided Loss for Accurate Land Title Deed Segmentation

open access: yesIEEE Access
Accurately segmenting land boundaries from Thai land title deeds is crucial for reliable land management and legal processes, but remains challenging due to low-quality scans, diverse layouts, and complex overlapping elements in documents.
Teerapong Panboonyuen   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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