Results 181 to 190 of about 495,798 (246)

Enhancing precision in robotic navigated minimally invasive transforaminal lumbar interbody fusion using a streamlined surgical workflow: a technical note. [PDF]

Brain Spine
Vadalà G, Russo F, Papalia GF, Ambrosio L, Franco D, Maltese G, Nardi N, Papalia R, Denaro V.   +8 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Regarding Emitter Positioning for Nanoflow Electrospray Ionization with a High-Capacity Inlet Capillary. [PDF]

J Am Soc Mass Spectrom
Lancaster NM, Quarmby ST, Overmyer KA, Coon JJ.   +3 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Prone positioning in pediatric acute respiratory distress syndrome: a systematic review and meta-analysis of randomized controlled trials. [PDF]

Front Pediatr
Al-Sofyani KA, Uddin MS, Alasnag M.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Research on Adaptive Cooperative Positioning Algorithm for Underwater Robots Based on Dolphin Group Cooperative Mechanism. [PDF]

Biomimetics (Basel)
Fan S, Chang J, Wang Z, Ding M, Sun H, Zhao Y.   +5 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Correction: Survey on positioning technology based on signal of opportunity from low earth orbit

Frontiers in Physics
Jiawei He, Jiawei He, Shaojie Ni, Shaojie Ni, Honglei Lin, Honglei Lin, Zhe Liu, Zhe Liu, Zhibin Xiao, Zhibin Xiao   +9 more
doaj   +1 more source

Impact of lithotomy position on ureteral course and psoas muscle: a combined survey and radiological evaluation by the EAU Endourology & YAU Endourology working groups. [PDF]

World J Urol
Sener TE, Ulker ND, Altuntas T, Gokmen E, Tsaturyan A, Pietropaolo A, Martinez BB, Angerri O, Skolarikos A, Somani BK, Traxer O.   +10 more
europepmc   +1 more source